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Property and Equipment, Net - Component of Property and Equipment, Net (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Property Plant And Equipment [Line Items]    
Manufacturing equipment $ 12,532 $ 13,884
Lab equipment 2,492 2,888
Computer equipment 5,336 5,255
Furniture and fixtures 2,463 2,510
Leasehold improvements 27,634 28,417
Assets in progress 9,941 1,024
Property, Plant and Equipment, Gross 60,398 53,978
Less accumulated depreciation and amortization (25,378) (23,411)
Total $ 35,020 $ 30,567
Manufacturing Equipment | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 5 years  
Manufacturing Equipment | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 13 years 14 years
Lab Equipment | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 5 years  
Lab Equipment | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 13 years 13 years
Computer Equipment    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 3 years 3 years
Furniture and Fixtures | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 3 years  
Furniture and Fixtures | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 13 years 13 years
Leasehold Improvements | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 2 years  
Leasehold Improvements | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 10 years 12 years