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Revenue Recognition - Summary of Product Revenue Allowance and Reserve Categories (Detail) - HEPLISAV-B - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Accounts Receivable Reserves
Valuation And Qualifying Accounts Disclosure [Line Items]
Balance at Beginning of Period	$ 2,836	$ 2,701
Provisions related to current period sales	18,209	11,417
Credit or payments made during the period	(17,222)	(11,282)
Balance at End of Period	3,823	2,836
Revenue Reserve Accruals
Valuation And Qualifying Accounts Disclosure [Line Items]
Balance at Beginning of Period	6,040	3,893
Provisions related to current period sales	13,077	6,694
Credit or payments made during the period	(10,864)	(4,547)
Balance at End of Period	$ 8,253	$ 6,040