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Common Stock - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 1 Months Ended 12 Months Ended
Feb. 28, 2022
Aug. 06, 2020
Aug. 31, 2021
May 31, 2020
Aug. 31, 2019
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Jun. 30, 2021
Nov. 03, 2017
Class Of Stock [Line Items]                    
Common stock, shares outstanding           122,945,357 110,190,000      
Issuance of common stock and preferred stock (in shares)         18,525,000          
Common stock, par value         $ 0.001 $ 0.001        
Preferred stock, par value           $ 0.001        
Proceeds from issuances of common stock, net           $ 28,156 $ 108,538 $ 65,948    
Preferred stock deemed dividend           $ 0 $ 0 $ 3,267    
Number of common stock warrants exercised           3,958,650,000   0    
Number of shares             0      
Less: removal of change in fair value of warrant liability           $ 49,354 $ (4,124) $ 7,500    
Subsequent Event                    
Class Of Stock [Line Items]                    
Number of common stock warrants exercised 1,882,600                  
Cash Settlement $ 8,500                  
Common Stock                    
Class Of Stock [Line Items]                    
Number of common stock allowed to purchase     4,140,000              
Warrants                    
Class Of Stock [Line Items]                    
Number of shares           1,883,000        
Fair value of derivative liability           $ 18,000   10,700    
Warrants Called for purchase           1,883,000        
Warrants | Other Nonoperating Income (Expense)                    
Class Of Stock [Line Items]                    
Less: removal of change in fair value of warrant liability           $ 49,400 $ 4,100 $ 7,500    
Bain Life Sciences                    
Class Of Stock [Line Items]                    
Net cash proceeds received from issuance or sale of equity         $ 35,000          
Bain Life Sciences | Common Stock                    
Class Of Stock [Line Items]                    
Warrants Called for purchase                 2,916,250,000  
Proceeds From Warrants Sale                 11,800,000  
Offering                    
Class Of Stock [Line Items]                    
Issuance of common stock and preferred stock (in shares)       2,100,000            
Common stock, par value       $ 0.001            
Price of common stock       $ 5.00            
Net cash proceeds received from issuance or sale of equity       $ 75,400 $ 65,600          
Offering | Bain Capital Life Sciences Fund, L.P                    
Class Of Stock [Line Items]                    
Issuance of common stock and preferred stock (in shares)       1,000,000            
2017 ATM Agreement                    
Class Of Stock [Line Items]                    
Issuance of common stock and preferred stock (in shares)           2,878,567,000        
Proceeds from issuances of common stock, net           $ 28,200        
Remaining proceeds from common stock, under sales agreement           $ 120,500        
Series B Convertible Preferred Stock                    
Class Of Stock [Line Items]                    
Issuance of common stock and preferred stock (in shares)     4,140   4,840,000          
Preferred stock, par value         $ 0.001          
Preferred stock, shares outstanding           0 4,000      
Maximum                    
Class Of Stock [Line Items]                    
Common stock sales agreement aggregate sales proceeds   $ 150,000                
Maximum | Warrants                    
Class Of Stock [Line Items]                    
Percentage of common stock held not to exceed for warrant exercises           19.99%        
Maximum | Offering                    
Class Of Stock [Line Items]                    
Issuance of common stock and preferred stock (in shares)       16,100,000            
Warrant issued         5,841,250          
Maximum | 2017 ATM Agreement                    
Class Of Stock [Line Items]                    
Commission on gross sales proceeds of common stock                   3.00%
Minimum | Warrants                    
Class Of Stock [Line Items]                    
Percentage of common stock to be held for exercise of warrants           4.99%