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Income Taxes - Additional Information (Detail) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Income Tax Disclosure [Line Items]      
Provision for income taxes $ 808,000 $ 0 $ 0
Increase (decrease) in valuation allowance 86,800,000 19,000,000.0  
Net operating loss carryforwards 333,400,000    
Unrecognized tax benefits 5,615,000 10,565,000  
Unrecognized tax benefits would affect the effective tax rate 0    
Interest related to unrecognized tax benefits 0 $ 0  
Penalties related to unrecognized tax benefits 200,000    
Federal      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards $ 303,800,000    
Federal | Minimum      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards, expiration year 2022    
Federal | Research And Development Tax Credits      
Income Tax Disclosure [Line Items]      
Tax credit carryforward amount $ 1,900,000    
Federal | Research And Development Tax Credits | Minimum      
Income Tax Disclosure [Line Items]      
Tax credit carryforward amount, expiration year 2022    
Federal | Research And Development Tax Credits | Maximum      
Income Tax Disclosure [Line Items]      
Tax credit carryforward amount, expiration year 2041    
California and Other States      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards $ 345,900,000    
California and Other States | Minimum      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards, expiration year 2022    
California and Other States | Maximum      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards, expiration year 2041    
California State | Research And Development Tax Credits      
Income Tax Disclosure [Line Items]      
Tax credit carryforward amount $ 19,600,000    
Foreign      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards $ 3,500,000