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Organization and Summary of Significant Accounting Policies - Additional Information (Detail) $ in Thousands | 3 Months Ended |  |
--- | --- | --- | ---
Mar. 31, 2022 USD ($) Segment | Mar. 31, 2021 USD ($) | Dec. 31, 2021 USD ($) | May 31, 2021 USD ($)
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Number of operating segment | Segment | 1 |  |  |
Long-term debt, net of debt discount | $ 4,741 |  | $ 5,010 |
Net income | 32,859 | $ 891 |  |
Inventory reserve | $ 0 | 0 |  |
Maximum |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Expected period of payment to be received | 1 year |  |  |
2.50% Convertible Senior Notes Due 2026 |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Aggregate principal amount | $ 225,500 | $ 158,800 |  | $ 200,000
Debt interest rate | 2.50% |  |  | 2.50%
Long-term debt, net of debt discount | $ 4,700 |  |  |
Debt maturity date | May 15, 2026 |  |  |
HEPLISAV-B |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Minimum age approved for vaccine prevention of infection caused | 18 years |  |  |

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