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Cash, Cash Equivalents, Restricted Cash and Marketable Securities - Summary of Cash, Cash Equivalents and Marketable Securities (Detail) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2022 | Dec. 31, 2021
Cash and Cash Equivalents |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | $ 179,420 | $ 436,189
Unrealized Gains | 1 |
Unrealized Losses |  |
Estimated Fair Value | 179,421 | 436,189
Marketable Securities Available-for-Sale |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 325,067 | 109,760
Unrealized Gains |  | 9
Unrealized Losses | (1,272) | (8)
Estimated Fair Value | 323,795 | 109,761
Marketable Securities Available-for-Sale | Cash and Cash Equivalents |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 504,487 | 545,949
Unrealized Gains | 1 | 9
Unrealized Losses | (1,272) | (8)
Estimated Fair Value | 503,216 | 545,950
Cash | Cash and Cash Equivalents |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 8,386 | 6,995
Unrealized Gains |  |
Unrealized Losses |  |
Estimated Fair Value | 8,386 | 6,995
Money Market Funds | Cash and Cash Equivalents |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 146,046 | 429,194
Unrealized Gains |  |
Unrealized Losses |  |
Estimated Fair Value | 146,046 | 429,194
U.S. Treasuries | Marketable Securities Available-for-Sale |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 25,087 | 4,005
Unrealized Gains |  |
Unrealized Losses | (11) | (1)
Estimated Fair Value | 25,076 | 4,004
U.S. Government Agency Securities | Marketable Securities Available-for-Sale |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 16,533 | 26,555
Unrealized Gains |  |
Unrealized Losses | (14) | (7)
Estimated Fair Value | 16,519 | 26,548
Corporate Debt Securities | Cash and Cash Equivalents |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 24,988 |
Unrealized Gains | 1 |
Unrealized Losses |  |
Estimated Fair Value | 24,989 |
Corporate Debt Securities | Marketable Securities Available-for-Sale |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 283,447 | 79,200
Unrealized Gains |  | 9
Unrealized Losses | (1,247) |
Estimated Fair Value | $ 282,200 | $ 79,209

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