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Cash, Cash Equivalents, Restricted Cash and Marketable Securities - Summary of Cash, Cash Equivalents and Marketable Securities (Detail) - USD ($) $ in Thousands	3 Months Ended	12 Months Ended
	Mar. 31, 2022	Dec. 31, 2021
Cash and Cash Equivalents
Cash Cash Equivalents And Marketable Securities [Line Items]
Amortized Cost	$ 179,420	$ 436,189
Unrealized Gains	1
Unrealized Losses
Estimated Fair Value	179,421	436,189
Marketable Securities Available-for-Sale
Cash Cash Equivalents And Marketable Securities [Line Items]
Amortized Cost	325,067	109,760
Unrealized Gains		9
Unrealized Losses	(1,272)	(8)
Estimated Fair Value	323,795	109,761
Marketable Securities Available-for-Sale | Cash and Cash Equivalents
Cash Cash Equivalents And Marketable Securities [Line Items]
Amortized Cost	504,487	545,949
Unrealized Gains	1	9
Unrealized Losses	(1,272)	(8)
Estimated Fair Value	503,216	545,950
Cash | Cash and Cash Equivalents
Cash Cash Equivalents And Marketable Securities [Line Items]
Amortized Cost	8,386	6,995
Unrealized Gains
Unrealized Losses
Estimated Fair Value	8,386	6,995
Money Market Funds | Cash and Cash Equivalents
Cash Cash Equivalents And Marketable Securities [Line Items]
Amortized Cost	146,046	429,194
Unrealized Gains
Unrealized Losses
Estimated Fair Value	146,046	429,194
U.S. Treasuries | Marketable Securities Available-for-Sale
Cash Cash Equivalents And Marketable Securities [Line Items]
Amortized Cost	25,087	4,005
Unrealized Gains
Unrealized Losses	(11)	(1)
Estimated Fair Value	25,076	4,004
U.S. Government Agency Securities | Marketable Securities Available-for-Sale
Cash Cash Equivalents And Marketable Securities [Line Items]
Amortized Cost	16,533	26,555
Unrealized Gains
Unrealized Losses	(14)	(7)
Estimated Fair Value	16,519	26,548
Corporate Debt Securities | Cash and Cash Equivalents
Cash Cash Equivalents And Marketable Securities [Line Items]
Amortized Cost	24,988
Unrealized Gains	1
Unrealized Losses
Estimated Fair Value	24,989
Corporate Debt Securities | Marketable Securities Available-for-Sale
Cash Cash Equivalents And Marketable Securities [Line Items]
Amortized Cost	283,447	79,200
Unrealized Gains		9
Unrealized Losses	(1,247)
Estimated Fair Value	$ 282,200	$ 79,209

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