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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Operating activities    
Net income $ 161,614 $ 5,364
Adjustments to reconcile net income to net cash (used in) provided by operating activities:    
Depreciation and amortization 2,085 2,202
Amortization of right-of-use assets and loss on disposal of property and equipment 1,644 1,326
(Accretion of discounts) amortization of premium on marketable securities (498) 369
Loss on debt extinguishment 0 5,232
Change in fair value of warrant liability (1,801) 23,455
Stock compensation expense 15,575 9,747
Non-cash interest expense 540 2,806
Gain on sale of assets (Note 5) (1,000) 0
Changes in operating assets and liabilities:    
Accounts and other receivables, net (42,426) (83,239)
Inventories, net (12,644) (22,762)
Prepaid manufacturing 105,178 (6,875)
Prepaid expenses and other current assets (60,774) (247)
Other assets 35 (265)
Accounts payable 2,319 7,209
CEPI accrual (Note 6) (21,478) 0
Lease liabilities (1,678) (1,554)
Deferred revenue (157,866) 91,345
Long Term Deferred Revenue 0 106,950
Accrued liabilities and other liabilities (22,617) 7,757
Net cash provided by (used in) operating activities (33,792) 148,820
Investing activities    
Purchases of marketable securities (313,660) (164,928)
Proceeds from maturities and redemptions of marketable securities 152,950 81,355
Purchases of property and equipment, net (4,271) (2,812)
Proceeds from sale of assets, net of transaction costs 1,000  
Net cash used in investing activities (163,981) (86,385)
Financing activities    
Proceeds from issuance of common stock, net 0 28,156
Proceeds from issuance of Convertible Notes, net 0 219,822
Purchases of capped call options 0 (27,240)
Repayment of long-term debt 0 (190,194)
Proceeds from warrants exercises 8,455 3,376
Proceeds from exercise of stock options and restricted stock awards, net 2,150 1,335
Proceeds from Employee Stock Purchase Plan 710 383
Net cash provided by financing activities 11,315 35,638
Effect of exchange rate changes on cash, cash equivalents and restricted cash (657) (546)
Net (decrease) increase in cash, cash equivalents and restricted cash (187,115) 97,527
Cash, cash equivalents and restricted cash at beginning of period 436,408 32,310
Cash, cash equivalents and restricted cash at end of period 249,293 129,837
Supplemental disclosure of cash flow information    
Cash paid during the period for income taxes 509 0
Cash paid during the period for interest 2,819 2,053
Non-cash investing and financing activities:    
Purchases of property and equipment, not yet paid 1,214 2,131
Right-of-use assets obtained in exchange of lease liabilities $ 1,767 $ 0