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v3.22.2.2

Organization and Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) | 3 Months Ended | 9 Months Ended |  |
--- | --- | --- | --- | ---
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | Dec. 31, 2021 | May 31, 2021
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |
Long-term debt, net of debt discount | $ 4,197,000 |  | $ 4,197,000 |  | $ 5,010,000 |
Inventory write-off recognized |  |  | 14,500,000 |  |  |
Net income (loss) | 63,809,000 | $ (28,430,000) | $ 225,423,000 | $ (23,066,000) |  |
Maximum |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |
Expected period of payment to be received |  |  | 1 year |  |  |
2.50% Convertible Senior Notes Due 2026 |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |
Aggregate principal amount | $ 225,500,000 |  | $ 225,500,000 |  |  | $ 200,000,000.0
Debt interest rate | 2.50% |  | 2.50% |  |  | 2.50%
Long-term debt, net of debt discount | $ 4,200,000 |  | $ 4,200,000 |  |  |
Debt maturity date |  |  | May 15, 2026 |  |  |
HEPLISAV-B |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |
Minimum age approved for vaccine prevention of infection caused |  |  | 18 years |  |  |
Increase in revenue adjustment |  |  | $ 700,000 |  |  |
Inventory reserve | 0 | 0 | 0 | 0 |  |
CpG 1018 adjuvant |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |
Inventory reserve | $ 0 | $ 0 | $ 0 | $ 0 |  |

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