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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
shares in Thousands, $ in Thousands
Total
Common Stock
Preferred Stock
Additional Paid-in Capital
Accumulated Other Comprehensive (Loss) Income
Accumulated Deficit
Beginning Balances at Dec. 31, 2020 $ 58,693 $ 110 $ 0 $ 1,352,374 $ 273 $ (1,294,064)
Beginning Balances (in shares) at Dec. 31, 2020   110,190 4      
Issuance of common stock upon exercise of stock options and/or release of restricted stock awards, net, shares   1,415        
Issuance of common stock upon exercise of stock options and/or release of restricted stock awards, net, amount 5,317 $ 2   5,315    
Issuance of common stock upon exercise of warrants (Shares)   946        
Issuance of common stock upon exercise of warrants 11,553 $ 1   11,552    
Conversion of preferred stock, shares   4,140 (4)      
Conversion of preferred stock, amount   $ 4   (4)    
Issuance of common stock under Employee Stock Purchase Plan 841     841    
Issuance of common stock under Employee Stock Purchase Plan (in shares)   217        
Issuance of common stock, net of issuance costs, in conjunction with an underwritten public offering and an At Market Sales Agreement 28,156 $ 3   28,153    
Issuance of common stock, net of issuance costs, in conjunction with an underwritten public offering and an At Market Sales Agreement (Shares)   2,879        
Issuance of capped call options (see Note 10) (27,240)     (27,240)    
Stock compensation expense 15,123     15,123    
Total other comprehensive income (Loss) (1,801)       (1,801)  
Net income (loss) (23,066)         (23,066)
Ending Balances at Sep. 30, 2021 67,576 $ 120 $ 0 1,386,114 (1,528) (1,317,130)
Ending Balances (in shares) at Sep. 30, 2021   119,787 0      
Beginning Balances at Jun. 30, 2021 83,380 $ 114 1,372,679 (713) (1,288,700)
Beginning Balances (in shares) at Jun. 30, 2021   114,756 4      
Issuance of common stock upon exercise of stock options and/or release of restricted stock awards, net, shares   582        
Issuance of common stock upon exercise of stock options and/or release of restricted stock awards, net, amount 3,982 $ 2   3,980    
Issuance of common stock upon exercise of warrants (Shares)   196        
Issuance of common stock upon exercise of warrants 3,625     3,625    
Conversion of preferred stock, shares   4,140 (4)      
Conversion of preferred stock, amount   $ 4   (4)    
Issuance of common stock under Employee Stock Purchase Plan 458     458    
Issuance of common stock under Employee Stock Purchase Plan (in shares)   113        
Stock compensation expense 5,376     5,376    
Total other comprehensive income (Loss) (815)       (815)  
Net income (loss) (28,430)         (28,430)
Ending Balances at Sep. 30, 2021 67,576 $ 120 $ 0 1,386,114 (1,528) (1,317,130)
Ending Balances (in shares) at Sep. 30, 2021   119,787 0      
Beginning Balances at Dec. 31, 2021 222,374 $ 123 $ 0 1,441,868 (2,266) (1,217,351)
Beginning Balances (in shares) at Dec. 31, 2021   122,945 0      
Issuance of common stock upon exercise of stock options and/or release of restricted stock awards, net, shares   2,603        
Issuance of common stock upon exercise of stock options and/or release of restricted stock awards, net, amount 9,487 $ 2   9,485    
Issuance of common stock upon exercise of warrants (Shares)   1,879        
Issuance of common stock upon exercise of warrants 24,670 $ 2   24,668    
Issuance of common stock under Employee Stock Purchase Plan 1,430     1,430    
Issuance of common stock under Employee Stock Purchase Plan (in shares)   154        
Stock compensation expense 24,188     24,188    
Total other comprehensive income (Loss) (6,996)       (6,996)  
Net income (loss) 225,423         225,423
Ending Balances at Sep. 30, 2022 500,576 $ 127 $ 0 1,501,639 (9,262) (991,928)
Ending Balances (in shares) at Sep. 30, 2022   127,581 0      
Beginning Balances at Jun. 30, 2022 422,799 $ 126 1,484,970 (6,560) (1,055,737)
Beginning Balances (in shares) at Jun. 30, 2022   126,439 0      
Issuance of common stock upon exercise of stock options and/or release of restricted stock awards, net, shares   1,070        
Issuance of common stock upon exercise of stock options and/or release of restricted stock awards, net, amount 7,337 $ 1   7,336    
Issuance of common stock under Employee Stock Purchase Plan 720     720    
Issuance of common stock under Employee Stock Purchase Plan (in shares)   72        
Stock compensation expense 8,613     8,613    
Total other comprehensive income (Loss) (2,702)       (2,702)  
Net income (loss) 63,809         63,809
Ending Balances at Sep. 30, 2022 $ 500,576 $ 127 $ 0 $ 1,501,639 $ (9,262) $ (991,928)
Ending Balances (in shares) at Sep. 30, 2022   127,581 0