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Inventories, Net - Additional Information (Detail) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021
Inventory [Line Items] |  |
Finished goods | $ 9,995 | $ 19,950
Inventory write-offs recognized | 34,300 | 0
Prepaid manufacturing | 0 | 159,655
CpG 1018 Adjuvant Inventory |  |
Inventory [Line Items] |  |
Finished goods |  | 1,300
Inventory write-offs recognized | 34,300 |
Prepaid manufacturing | 0 | 159,700
HEPLISAV-B |  |
Inventory [Line Items] |  |
Finished goods inventory | $ 10,000 | $ 18,600

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