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Commitments and Contingencies - Additional Information (Detail) $ in Thousands, € in Millions | 1 Months Ended | 12 Months Ended |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Aug. 31, 2020 USD ($) | Jul. 31, 2019 | Nov. 30, 2009 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Dec. 31, 2022 EUR (€) | May 31, 2021 USD ($) | Mar. 29, 2019 USD ($) | Feb. 20, 2018 USD ($) | Dec. 31, 2004 EUR (€)
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Lease expiration date |  |  |  | Mar. 31, 2031 |  |  |  |  |  |  |
Sublease income |  |  |  | $ 7,685 | $ 7,735 | $ 7,706 |  |  |  |  |
Cash paid for amounts included in the measurement of operating lease liabilities |  |  |  | 6,800 | 7,000 | 6,900 |  |  |  |  |
Long-term debt, net of debt discount |  |  |  | $ 3,922 | 5,010 |  |  |  |  |  |
Option to extend |  |  |  | The subtenant has no option to extend the sublease term. |  |  |  |  |  |  |
Tenant improvement allowance |  |  |  | $ 0 | 0 | (1,137) |  |  |  |  |
Percentage of excess rent paid to landlord |  |  |  | 50.00% |  |  | 50.00% |  |  |  |
Non-cancelable purchase and other commitments |  |  |  | $ 43,408 |  |  |  |  |  |  |
Liability under agreement |  |  |  | 404,837 | 816,872 |  |  |  |  |  |
Gain on sale of assets |  |  |  | 1,000 | 1,000 | 6,851 |  |  |  |  |
Selling, general and administrative |  |  |  | 131,408 | 100,156 | $ 79,256 |  |  |  |  |
Current liabilities |  |  |  | 150,074 | 556,402 |  |  |  |  |  |
2.50% Convertible Senior Notes Due 2026 |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Principal amount |  |  |  | 225,500 |  |  |  | $ 200,000 |  |  |
Long-term debt, net of debt discount |  |  |  | $ 3,900 |  |  |  |  |  |  |
Debt maturity date |  |  |  | May 15, 2026 |  |  |  |  |  |  |
Asset Purchase Agreement |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Current liabilities |  |  |  | $ 0 |  |  |  |  |  |  |
Symphony Dynamo Holdings Llc |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
License arrangement contingent consideration percentage |  |  | 50.00% |  |  |  |  |  |  |  |
License arrangement upfront payment |  |  | $ 50,000 |  |  |  |  |  |  |  |
Trisalus Life Sciences |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Payment to holdings | $ 2,500 |  |  |  |  |  |  |  |  |  |
Payment received for pre-commercialization milestone |  |  |  | 1,000 | 1,000 |  |  |  |  |  |
Trisalus Life Sciences | Asset Purchase Agreement |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Payment made for pre-commercialization milestone |  |  |  | $ 500 | $ 500 |  |  |  |  |  |
Deutsche Bank Securities |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Financial instruments owned at fair value | € |  |  |  |  |  |  | € 0.2 |  |  |  |
Deutsche Bank Securities | Letter of Credit |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Financial instruments owned at fair value | € |  |  |  |  |  |  |  |  |  |  | € 0.2
CRG Servicing LLC |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Debt maturity date |  |  |  | Dec. 31, 2023 |  |  |  |  |  |  |
Maximum borrowing capacity |  |  |  |  |  |  |  |  |  | $ 175,000 |
Current borrowing capacity |  |  |  |  |  |  |  |  | $ 75,000 | $ 100,000 |
Emeryville, California (Premises) |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Existence of option to extend |  | false |  |  |  |  |  |  |  |  |
Emeryville, California and Dusseldorf, Germany |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Lease option to extend |  |  |  | Certain of these leases also include renewal options at our election to renew or extend the lease for two successive five-year terms |  |  |  |  |  |  |
Emeryville, California and Dusseldorf, Germany | Maximum |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Lease term |  |  |  | 12 years |  |  | 12 years |  |  |  |
Emeryville, California and Dusseldorf, Germany | Minimum |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Lease term |  |  |  | 3 years |  |  | 3 years |  |  |  |
Powell Street Sublease | Emeryville, California (Premises) |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Existence of option to extend |  |  |  |  |  | false |  |  |  |  |

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