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Summary of Significant Accounting Policies - Additional Information (Detail) $ in Thousands | 12 Months Ended |
--- | --- | ---
Dec. 31, 2022 USD ($) Segment | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | May 31, 2021 USD ($)
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Number of operating segment | Segment | 1 |  |  |
Long-term debt, net of debt discount | $ 3,922 | $ 5,010 |  |
Net income (loss) | 293,156 | 76,713 | $ (75,240) |
Unrealized foreign currency translation (loss) gain | (1,800) | (2,500) | 2,700 |
Currency transaction gain (loss) | $ 100 | $ 900 | (800) |
Percentage of long lived assets | 34.00% | 43.00% |  |
Inventory write-off | $ 34,288 | $ 2,588 | $ 0 |
Inventory write-offs recognized | 34,300 | $ 0 |  |
Goodwill impairment | 0 |  |  |
2.50% Convertible Senior Notes Due 2026 |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Principal amount | $ 225,500 |  |  | $ 200,000
Debt interest rate | 2.50% |  |  | 2.50%
Long-term debt, net of debt discount | $ 3,900 |  |  |
Debt maturity date | May 15, 2026 |  |  |
Product | Credit Concentration Risk |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Concentration risk, customer | one |  |  |
Product | Trade Receivable | Credit Concentration Risk |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Concentration risk, customer |  | one |  |
Product | Trade Receivable | Customer Concentration Risk |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Concentration risk, percentage | 100.00% | 94.00% |  |
HEPLISAV-B |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Inventory write-off | $ 0 | $ 2,600 |  |
HEPLISAV-B | Credit Concentration Risk |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Concentration risk, customer | three | three |  |
HEPLISAV-B | Trade Receivable | Credit Concentration Risk |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Concentration risk, percentage | 78.00% | 76.00% |  |
Maximum |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Cash equivalents original maturity period | 3 months |  |  |
Percentage of long lived assets | 10.00% | 10.00% |  |
Expected period of payment to be received | 1 year |  |  |
Dynavax GmbH |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Cumulative translation adjustment | $ (4,000) | $ (2,300) |  |

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