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Inventories, Net - Additional Information (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Inventory [Line Items]    
Finished goods $ 9,995 $ 19,950
Inventory write-offs recognized 34,300 0
Prepaid manufacturing 0 159,655
CpG 1018 Adjuvant Inventory    
Inventory [Line Items]    
Finished goods   1,300
Inventory write-offs recognized 34,300  
Prepaid manufacturing 0 159,700
HEPLISAV-B    
Inventory [Line Items]    
Finished goods inventory $ 10,000 $ 18,600