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Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
Common Stock
Preferred Stock
Additional Paid-in Capital
Accumulated Other Comprehensive (Loss) Income
Accumulated Deficit
Beginning Balances at Dec. 31, 2019 $ 8,290 $ 84 $ 1,229,417 $ (2,387) $ (1,218,824)
Beginning Balances (in shares) at Dec. 31, 2019   83,871,000 5,000      
Conversion of Preferred Stock 1 $ 1        
Stock Issued During Period, Shares, Conversion of Convertible Securities   700,000 (1,000)      
Issuance (withholding) of common stock upon exercise of stock options and restricted stock awards, net 289 $ 1   288    
Issuance (withholding) of common stock upon exercise of stock options and restricted stock awards, net (in shares)   1,209,000        
Issuance of common stock, net of issuance costs, in conjunction with an underwritten public offering and an At Market Sales Agreement (Shares)   24,215,000        
Issuance of common stock, net of issuance costs, in conjunction with an underwritten public offering and an At Market Sales Agreement 108,537 $ 24   108,513    
Issuance of common stock under Employee Stock Purchase Plan 672     672    
Issuance of common stock under Employee Stock Purchase Plan (in shares)   195,000        
Stock compensation expense 13,484     13,484    
Total other comprehensive income (loss) 2,660       2,660  
Net income (loss) (75,240)         (75,240)
Ending Balances at Dec. 31, 2020 58,693 $ 110 $ 0 1,352,374 273 (1,294,064)
Ending Balances (in shares) at Dec. 31, 2020   110,190,000 4,000      
Conversion of Preferred Stock   $ 4   (4)    
Stock Issued During Period, Shares, Conversion of Convertible Securities   4,140,000        
Stock Redeemed During Period, Shares, Conversion of Convertible Securities (in shares)     (4,000)      
Issuance (withholding) of common stock upon exercise of stock options and restricted stock awards, net 6,577 $ 2   6,575    
Issuance (withholding) of common stock upon exercise of stock options and restricted stock awards, net (in shares)   1,560,000        
Issuance of common stock, net of issuance costs, in conjunction with an underwritten public offering and an At Market Sales Agreement (Shares)   2,879,000        
Issuance of common stock, net of issuance costs, in conjunction with an underwritten public offering and an At Market Sales Agreement 28,156 $ 3   28,153    
Issuance of common stock under Employee Stock Purchase Plan 841     841    
Issuance of common stock under Employee Stock Purchase Plan (in shares)   217,000        
Issuance of common stock upon exercise of warrants (Shares)   3,959,000        
Issuance of common stock upon exercise of warrants 59,888 $ 4   59,884    
Issuance of capped call options (see Note 10) (27,240)     (27,240)    
Stock compensation expense 21,285     21,285    
Total other comprehensive income (loss) (2,539)       (2,539)  
Net income (loss) 76,713         76,713
Ending Balances at Dec. 31, 2021 222,374 $ 123 $ 0 1,441,868 (2,266) (1,217,351)
Ending Balances (in shares) at Dec. 31, 2021   122,945,000 0      
Issuance (withholding) of common stock upon exercise of stock options and restricted stock awards, net 9,640 $ 3   9,637    
Issuance (withholding) of common stock upon exercise of stock options and restricted stock awards, net (in shares)   2,626,000        
Issuance of common stock under Employee Stock Purchase Plan 1,430     1,430    
Issuance of common stock under Employee Stock Purchase Plan (in shares)   154,000        
Issuance of common stock upon exercise of warrants (Shares)   1,879,000        
Issuance of common stock upon exercise of warrants 24,670 $ 2   24,668    
Stock compensation expense 32,915     32,915    
Total other comprehensive income (loss) (3,172)       (3,172)  
Net income (loss) 293,156         293,156
Ending Balances at Dec. 31, 2022 $ 581,013 $ 128 $ 0 $ 1,510,518 $ (5,438) $ (924,195)
Ending Balances (in shares) at Dec. 31, 2022   127,604,000 0