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Revenue Recognition - Summary of Balances and Activities Deferred Revenue Accounts (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Deferred Revenue Arrangement [Line Items]    
Balance at Beginning of Period $ 349,864  
Balance at End of Period 0 $ 349,864
CpG 1018    
Deferred Revenue Arrangement [Line Items]    
Balance at Beginning of Period 349,864 38,212
Additions [1] 45,596 371,860
Subtractions [2] (45,955) (21,996)
Revenue recognized in the current period included in deferred revenue balance at the beginning of the period 349,505 38,212
Balance at End of Period 0 349,864
CpG 1018 | Long-term Deferred Revenue    
Deferred Revenue Arrangement [Line Items]    
Balance at Beginning of Period 5,385 0
Additions [1] 6,582 168,467
Subtractions [2] (11,967) (163,082)
Revenue recognized in the current period included in deferred revenue balance at the beginning of the period 0 0
Balance at End of Period $ 0 $ 5,385
[1] Additions are primarily payments received or invoices issued before we satisfy our performance obligations.
[2] Subtractions are primarily revenues recognized in the period and reclassification from long-term deferred revenue to CEPI accrual.