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Income Taxes - Additional Information (Detail) - USD ($)
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Line Items]      
Provision for income taxes $ 1,143,000 $ 808,000 $ 0
Increase (decrease) in valuation allowance 300,000 86,800,000  
Net operating loss carryforwards 353,500,000    
Unrecognized tax benefits 11,339,000 5,615,000 $ 10,565,000
Unrecognized tax benefits would affect the effective tax rate 0    
Interest related to unrecognized tax benefits 0 0  
Penalties related to unrecognized tax benefits 0 $ 200,000  
Federal      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards $ 96,300,000    
Federal | Minimum      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards, expiration year 2023    
Federal | Research And Development Tax Credits      
Income Tax Disclosure [Line Items]      
Tax credit carryforward amount $ 26,200,000    
Federal | Research And Development Tax Credits | Minimum      
Income Tax Disclosure [Line Items]      
Tax credit carryforward amount, expiration year 2023    
Federal | Research And Development Tax Credits | Maximum      
Income Tax Disclosure [Line Items]      
Tax credit carryforward amount, expiration year 2042    
California and Other States      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards $ 308,800,000    
California and Other States | Minimum      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards, expiration year 2023    
California and Other States | Maximum      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards, expiration year 2040    
California State | Research And Development Tax Credits      
Income Tax Disclosure [Line Items]      
Tax credit carryforward amount $ 22,100,000    
Foreign      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards $ 700,000