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Commitments and Contingencies - Additional Information (Detail) € in Millions | 1 Months Ended | 3 Months Ended |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
May 31, 2022 USD ($) | Sep. 30, 2021 USD ($) | Nov. 30, 2009 USD ($) | Mar. 31, 2023 USD ($) | Mar. 31, 2022 USD ($) | Dec. 31, 2023 | Mar. 31, 2023 EUR (€) | Dec. 31, 2022 USD ($) | May 31, 2021 USD ($) | Dec. 31, 2004 EUR (€)
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Lease expiration date |  |  |  | Mar. 31, 2031 |  |  |  |  |  |
Option to extend |  |  |  | The subtenant has no option to extend the sublease term |  |  |  |  |  |
Sublease income |  |  |  | $ 1,598,000 | $ 1,609,000 |  |  |  |  |
Percentage of excess rent paid to landlord |  |  |  | 50.00% |  |  | 50.00% |  |  |
Cash paid for amounts included in the measurement of operating lease liabilities |  |  |  | $ 1,700,000 | 1,700,000 |  |  |  |  |
Long-term debt, net of debt discount |  |  |  | 3,645,000 |  |  |  | $ 3,922,000 |  |
Selling, general and administrative |  |  |  | 36,543,000 | $ 32,172,000 |  |  |  |  |
Liabilities, Current |  |  |  | 91,515,000 |  |  |  | 150,074,000 |  |
HEPLISAV-B |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Purchase Obligation, Total |  |  |  | 40,800,000 |  |  |  | 43,400,000 |  |
Non-cancelable purchase and other commitments |  |  |  | 40,800,000 |  |  |  | $ 43,400,000 |  |
Asset Purchase Agreement |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Liabilities, Current |  |  |  | 0 |  |  |  |  |  |
Symphony Dynamo Holdings LLC |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
License arrangement contingent consideration percentage |  |  | 50.00% |  |  |  |  |  |  |
License Arrangement Contingent Payment To Acquire License |  |  | $ 50,000,000 |  |  |  |  |  |  |
License arrangement upfront payment |  |  | $ 50,000,000 |  |  |  |  |  |  |
TriSalus |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Payment to holdings |  |  |  | 2,500,000 |  |  |  |  |  |
Payment received for Pre-commercialization milestone | $ 1,000,000.0 | $ 1,000,000.0 |  |  |  |  |  |  |  |
TriSalus | Asset Purchase Agreement |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Payment made for Pre-commercialization milestone | $ 500 | $ 500 |  |  |  |  |  |  |  |
Deutsche Bank Securities |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Financial Instruments, Owned, at Fair Value | € |  |  |  |  |  |  | € 0.2 |  |  |
Deutsche Bank Securities | Letter of Credit [Member] |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Financial Instruments, Owned, at Fair Value | € |  |  |  |  |  |  |  |  |  | € 0.2
2.50% Convertible Senior Notes Due 2026 |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Aggregate principal amount |  |  |  | 225,500,000 |  |  |  |  | $ 200,000,000.0 |
Long-term debt, net of debt discount |  |  |  | $ 3,600,000 |  |  |  |  |  |
Debt maturity date |  |  |  | May 15, 2026 |  |  |  |  |  |
Emeryville, California (Premises) |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
Lease option to extend |  |  |  | Certain of these leases also include options to renew or extend the lease for two successive five-year terms |  |  |  |  |  |
Maximum [Member] | Emeryville, California (Premises) |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
lease term |  |  |  |  |  | 12 years |  |  |  |
Minimum [Member] | Emeryville, California (Premises) |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |
lease term |  |  |  | 3 years |  |  | 3 years |  |  |

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