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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Operating activities    
Net (loss) income $ (24,332) $ 32,859
Adjustments to reconcile net (loss) income to net cash provided by (used in) operating activities:    
Depreciation and amortization 1,013 985
Amortization of right-of-use assets and loss on disposal of property and equipment 642 743
Accretion of discounts on marketable securities (3,498) (181)
Change in fair value of warrant liability 0 (1,801)
Stock-based compensation expense 10,034 7,646
Bad debt expense 12,313 0
Non-cash interest expense 1,686 1,680
Changes in operating assets and liabilities:    
Accounts and other receivables, net 30,336 (5,120)
Inventories, net 1,753 (17,703)
Prepaid manufacturing 0 21,325
Prepaid expenses and other current assets (1,304) (9,231)
Other assets 677 (49)
Accounts payable 4,096 16,938
CEPI accrual (Note 6) 0 (21,478)
Lease liabilities (793) (806)
Deferred revenue 0 (36,661)
Accrued liabilities and other liabilities (5,001) (39,589)
Net cash provided by (used in) operating activities 27,622 (50,443)
Investing activities    
Purchases of marketable securities (185,301) (250,375)
Proceeds from maturities of marketable securities 134,250 35,250
Purchases of property and equipment, net (1,283) (1,358)
Net cash used in investing activities (52,334) (216,483)
Financing activities    
Proceeds from warrants exercised 0 8,455
Proceeds from exercise of stock options and/or release of restricted stock awards, net 239 1,122
Proceeds from Employee Stock Purchase Plan 777 710
Payments for taxes related to net share settlement of RSUs (4,106) 0
Net cash (used in) provided by financing activities (3,090) 10,287
Effect of exchange rate changes on cash and cash equivalents, and restricted cash 151 (134)
Net decrease in cash and cash equivalents, and restricted cash (27,651) (256,773)
Cash and cash equivalents, and restricted cash at beginning of period 202,211 436,408
Cash and cash equivalents, and restricted cash at end of period 174,560 179,635
Supplemental disclosure of cash flow information    
Cash paid during the period for income taxes 32 87
Reclassification of contract asset from other current assets to other assets 71,307 0
Reclassification of CEPI accrual to CEPI accrual long-term (60,337) 0
Non-cash investing and financing activities:    
Purchases of property and equipment, not yet paid 926 2,007
Right-of-use assets obtained in exchange of operating lease liabilities $ 278 $ 1,173