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Revenue Recognition - Schedule of Revenues from Major Customers (Detail) - Product Concentration Risk [Member] - Revenue Benchmark [Member]
3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Largest Customer | HEPLISAV-B        
Concentration Risk [Line Items]        
Percentage of product revenue 24.00% 18.00% 24.00% 21.00%
Second Largest Customer | HEPLISAV-B        
Concentration Risk [Line Items]        
Percentage of product revenue 21.00% 18.00% 23.00% 18.00%
Third Largest Customer | HEPLISAV-B        
Concentration Risk [Line Items]        
Percentage of product revenue 18.00% 18.00% 17.00% 17.00%
Largest Collaboration Partner | CpG 1018        
Concentration Risk [Line Items]        
Percentage of product revenue 0.00% 41.00% 0.00% 38.00%
Second Largest Collaboration Partner | CpG 1018        
Concentration Risk [Line Items]        
Percentage of product revenue 0.00% 31.00% 0.00% 36.00%
Third largest collaboration partner | CpG 1018        
Concentration Risk [Line Items]        
Percentage of product revenue 0.00% 23.00% 0.00% 22.00%