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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Operating activities    
Net Income (Loss) $ (20,901) $ 161,614
Adjustments to reconcile net income to net cash (used in) provided by operating activities:    
Depreciation and amortization 2,113 2,085
Amortization of right-of-use assets and loss on disposal of property and equipment 1,335 1,644
Accretion of discounts on marketable securities (7,263) (498)
Change in fair value of warrant liability 0 (1,801)
Stock compensation expense 20,596 15,575
Bad debt expense (Note 6) 12,313 0
Non-cash interest expense 556 540
Gain on sale of assets (Note 5) 0 (1,000)
Changes in operating assets and liabilities:    
Accounts and other receivables, net 42,448 (42,426)
Inventories 6,358 (12,644)
Prepaid manufacturing 0 105,178
Prepaid expenses and other current assets (3,172) (60,774)
Other assets 703 35
Accounts payable (151) 2,319
CEPI accrual (Note 6) 0 (21,478)
Lease liabilities (1,679) (1,678)
Deferred revenue 0 (157,866)
Accrued liabilities and other liabilities 2,412 (22,617)
Net cash provided by (used in) operating activities 55,668 (33,792)
Investing activities    
Purchases of marketable securities (259,531) (313,660)
Proceeds from maturities of marketable securities 233,953 152,950
Purchases of property and equipment, net (2,034) (4,271)
Proceeds from sale of assets 0 1,000
Net cash used in investing activities (27,612) (163,981)
Financing activities    
Proceeds from warrants exercises 0 8,455
Proceeds from exercise of stock options and/or release of restricted stock awards, net 1,617 2,150
Proceeds from Employee Stock Purchase Plan 777 710
Payments for taxes related to net share settlement of RSUs (5,778) 0
Net cash provided by financing activities (3,384) 11,315
Effect of exchange rate changes on cash, cash equivalents and restricted cash 150 (657)
Net (decrease) increase in cash, cash equivalents and restricted cash 24,822 (187,115)
Cash, cash equivalents and restricted cash at beginning of period 202,211 436,408
Cash, cash equivalents and restricted cash at end of period 227,033 249,293
Supplemental disclosure of cash flow information    
Cash paid during the period for income taxes 710 509
Cash paid during the period for interest 2,819 2,819
Reclassification of contract asset from other current assets to other assets 71,307 0
Reclassification of CEPI accrual to CEPI accrual long-term (60,337) 0
Advance Payments forgiven per CEPI-Bio E Assignment Agreement (Note 6) (47,401) 0
Non-cash investing and financing activities:    
Purchases of property and equipment, not yet paid 540 1,214
Right-of-use assets obtained in exchange of lease liabilities $ 901 $ 1,767