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Commitments and Contingencies - Additional Information (Detail)
$ in Thousands, € in Millions
 1 Months Ended 3 Months Ended 6 Months Ended
May 31, 2022
USD ($)
Nov. 30, 2009
USD ($)
Jun. 30, 2023
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2023
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2023
EUR (€)
Dec. 31, 2022
USD ($)
May 31, 2021
USD ($)
Loss Contingencies [Line Items]                  
Lease expiration date         Mar. 31, 2031        
Option to extend         The subtenant has no option to extend the sublease term        
Sublease income     $ 1,993 $ 2,025 $ 3,591 $ 3,634      
Percentage of excess rent paid to landlord     50.00%   50.00%   50.00%    
Cash paid for amounts included in the measurement of operating lease liabilities         $ 3,500 $ 3,500      
Long-term debt, net of debt discount     $ 3,366   3,366     $ 3,922  
Liabilities     44,862   44,862     150,074  
H E P L I S A V B [Member]                  
Loss Contingencies [Line Items]                  
Non-cancelable purchase and other commitments     38,300   38,300     $ 43,400  
Asset Purchase Agreement                  
Loss Contingencies [Line Items]                  
Liabilities     0   0        
Symphony Dynamo Holdings LLC                  
Loss Contingencies [Line Items]                  
License arrangement contingent consideration percentage   50.00%              
License Arrangement Contingent Payment To Acquire License   $ 50,000              
TriSalus                  
Loss Contingencies [Line Items]                  
Payment to holdings         2,500        
Payment received for Pre-commercialization milestone $ 1,000                
TriSalus | Asset Purchase Agreement                  
Loss Contingencies [Line Items]                  
Payment made for Pre-commercialization milestone $ 500                
Deutsche Bank Securities                  
Loss Contingencies [Line Items]                  
Financial Instruments, Owned, at Fair Value | €             € 0.2    
Deutsche Bank Securities | Letter of Credit [Member]                  
Loss Contingencies [Line Items]                  
Financial Instruments, Owned, at Fair Value | €             € 0.2    
2.50% Convertible Senior Notes Due 2026                  
Loss Contingencies [Line Items]                  
Aggregate principal amount     225,500   225,500       $ 225,500
Long-term debt, net of debt discount     $ 3,400   $ 3,400        
California                  
Loss Contingencies [Line Items]                  
Lease option to extend         Certain of these leases also include options to renew or extend the lease for two successive five-year terms        
California | Maximum [Member]                  
Loss Contingencies [Line Items]                  
Initial lease term     12 years   12 years   12 years    
California | Minimum [Member]                  
Loss Contingencies [Line Items]                  
Initial lease term     3 years   3 years   3 years