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Revenue Recognition - Schedule of Revenues from Major Customers (Detail) - Product Concentration Risk [Member] - Revenue Benchmark [Member]	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Largest Customer | HEPLISAV-B
Concentration Risk [Line Items]
Percentage of product revenue	27.00%	23.00%	25.00%	20.00%
Second Largest Customer | HEPLISAV-B
Concentration Risk [Line Items]
Percentage of product revenue	25.00%	19.00%	24.00%	18.00%
Third Largest Customer | HEPLISAV-B
Concentration Risk [Line Items]
Percentage of product revenue	18.00%	18.00%	17.00%	17.00%
Largest Collaboration Partner | CpG 1018
Concentration Risk [Line Items]
Percentage of product revenue	0.00%	69.00%	0.00%	46.00%
Second Largest Collaboration Partner | CpG 1018
Concentration Risk [Line Items]
Percentage of product revenue	0.00%	22.00%	0.00%	33.00%
Third largest collaboration partner | CpG 1018
Concentration Risk [Line Items]
Percentage of product revenue	0.00%	9.00%	0.00%	15.00%

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- Definition

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