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Income taxes - Schedule of Component of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands | Dec. 31, 2023 | Dec. 31, 2022
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Deferred tax assets: |  |
Net operating loss carryforwards | $ 96,336 | $ 113,228
Research credit carryforwards | 34,940 | 33,444
Section 174 capitalization | 22,556 | 15,308
Lease liability | 8,868 | 9,530
Stock compensation | 10,572 | 7,780
Accruals and reserves | 15,808 | 9,089
Other | 348 | 337
Total deferred tax assets | 189,428 | 188,716
Less valuation allowance | (180,387) | (178,920)
Net deferred tax assets | 9,041 | 9,796
Deferred tax liabilities: |  |
Fixed assets | (2,667) | (2,916)
Operating lease right-of-use assets | (6,345) | (6,785)
Other | (29) | (95)
Total deferred tax liabilities | (9,041) | (9,796)
Net deferred tax assets | $ 0 | $ 0

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