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Commitments and Contingencies - Additional Information (Detail) $ in Thousands, € in Millions |  | 1 Months Ended | 3 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Mar. 07, 2024 USD ($) | Oct. 31, 2023 USD ($) | Sep. 30, 2023 USD ($) | May 31, 2022 USD ($) | Sep. 30, 2021 USD ($) | Aug. 31, 2020 USD ($) | Nov. 30, 2009 USD ($) | Mar. 31, 2024 USD ($) | Mar. 31, 2023 USD ($) | Mar. 31, 2024 EUR (€) | Feb. 22, 2024 ft² | Dec. 31, 2023 USD ($) | May 31, 2021 USD ($)
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Lease area | ft² |  |  |  |  |  |  |  |  |  |  | 75,662 |  |
Termination of sublease agreement | $ 3,500 |  |  |  |  |  |  |  |  |  |  |  |
Write-off of accrued balance | 4,800 |  |  |  |  |  |  |  |  |  |  |  |
Collection of termination payment | $ 1,300 |  |  |  |  |  |  |  |  |  |  |  |
Sublease (expense) income (Note 5) |  |  |  |  |  |  |  | $ 1,900 | $ 1,600 |  |  |  |
Cash paid for amounts included in the measurement of operating lease liabilities |  |  |  |  |  |  |  | 1,900 | 1,700 |  |  |  |
Long-term debt, net of debt discount |  |  |  |  |  |  |  | 2,516 |  |  |  | $ 2,802 |
Selling, general and administrative |  |  |  |  |  |  |  | 44,065 | $ 36,543 |  |  |  |
Aggregate minimum commitment |  |  |  |  |  |  |  | $ 7,400 |  |  |  | 7,400 |
Description of Avecia Supply Agreement |  |  |  |  |  |  |  | On September 7, 2023 (the “Effective Date”), we entered into an agreement (the “Avecia Supply Agreement”) with Nitto Denko Avecia Inc. (“Avecia”) for the manufacture and supply of our CpG 1018 adjuvant using a specific production process. Under the Avecia Supply Agreement, Avecia has agreed to produce and supply to us quantities of CpG 1018 adjuvant ordered by us after the Effective Date. Subject to certain conditions in the Avecia Supply Agreement, we are obligated to purchase all of our annual volume requirements of CpG 1018 adjuvant from Avecia up to a specified production capacity. We may alternatively order CpG 1018 adjuvant produced using a different production process pursuant to the existing supply agreement between us and Avecia dated October 1, 2012 (the “2012 Agreement”). Included in the balance of our material non-cancelable purchase and other commitments for the supply of HEPLISAV-B, as of March 31, 2024 and December 31, 2023, our aggregate minimum commitment for the supply of CpG 1018 adjuvant under the Avecia Supply Agreement totaled $7.4 million for each period, anticipated within the next 12 months. |  |  |  |  |
Liabilities, Current |  |  |  |  |  |  |  | $ 56,002 |  |  |  | 62,195 |
HEPLISAV-B |  |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Purchase Obligation, Total |  |  |  |  |  |  |  | 40,500 |  |  |  | 43,400 |
Non-cancelable purchase and other commitments |  |  |  |  |  |  |  | 40,500 |  |  |  | $ 43,400 |
Symphony Dynamo Holdings LLC |  |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
License arrangement contingent consideration percentage |  |  |  |  |  |  | 50.00% |  |  |  |  |  |
License Arrangement Contingent Payment To Acquire License |  |  |  |  |  |  | $ 50,000 |  |  |  |  |  |
License arrangement upfront payment |  |  |  |  |  |  | $ 50,000 |  |  |  |  |  |
TriSalus |  |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Payment to holdings |  |  |  |  |  | $ 2,500 |  |  |  |  |  |  |
Payment received for Pre-commercialization milestone |  |  | $ 1,000 | $ 1,000 | $ 1,000 |  |  |  |  |  |  |  |
TriSalus | Asset Purchase Agreement |  |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Payment made for Pre-commercialization milestone |  | $ 500 |  | $ 500 | $ 500 |  |  |  |  |  |  |  |
Deutsche Bank Securities |  |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Financial Instruments, Owned, at Fair Value | € |  |  |  |  |  |  |  |  |  | € 0.2 |  |  |
Deutsche Bank Securities | Letter of Credit [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Financial Instruments, Owned, at Fair Value | € |  |  |  |  |  |  |  |  |  | € 0.2 |  |  |
2.50% Convertible Senior Notes Due 2026 |  |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate principal amount |  |  |  |  |  |  |  | 225,500 |  |  |  |  | $ 225,500
Long-term debt, net of debt discount |  |  |  |  |  |  |  | $ 2,500 |  |  |  |  |
Debt maturity date |  |  |  |  |  |  |  | May 15, 2026 |  |  |  |  |
Emeryville, California (Premises) |  |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Lease option to extend |  |  |  |  |  |  |  | Certain of these leases also include options to renew or extend the lease for two successive five-year terms |  |  |  |  |
Maximum [Member] | Emeryville, California (Premises) |  |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
lease term |  |  |  |  |  |  |  | 12 years |  | 12 years |  |  |
Minimum [Member] | Emeryville, California (Premises) |  |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
lease term |  |  |  |  |  |  |  | 3 years |  | 3 years |  |  |

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