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Insider Trading Arrangements
 3 Months Ended 9 Months Ended
Sep. 30, 2024
shares
Sep. 30, 2024
shares
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement  
During our last fiscal quarter, our directors and officers (as defined in Rule 16a-1(f) under the Exchange Act) adopted or terminated the contracts, instructions or written plans for the purchase or sale of our securities set forth in the table below.
Type of Trading Arrangement
Name and PositionAction
Adoption/ Termination
Date
Rule 10b5-1*Non-Rule 10b5-1**Total Shares of Common Stock to be SoldTotal Shares of Common Stock to be PurchasedExpiration Date
Robert Janssen, M.D.,
Chief Medical Officer and Senior Vice President, Clinical Development, Medical and Regulatory Affairs
Termination (1)
July 26, 2024
X
311,535 shares of common stock underlying stock options
September 12, 2025, unless earlier terminated as outlined in the plan
Robert Janssen, M.D.,
Chief Medical Officer and Senior Vice President, Clinical Development, Medical and Regulatory Affairs
Adoption
August 8, 2024
X 
281,251 shares of common stock underlying stock options
 
November 13, 2025, unless earlier terminated as outlined in the plan
* Contract, instruction or written plan intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act.
** “Non-Rule 10b5-1 trading arrangement” as defined in Item 408(c) of Regulation S-K under the Exchange Act.
(1) Represents the termination of a written plan intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) adopted on May 30, 2024.
Non-Rule 10b5-1 Arrangement Adopted false  
Non-Rule 10b5-1 Arrangement Terminated false  
July 2024 Rule 105b-1 Plan [Member] | Robert Janssen [Member]    
Trading Arrangements, by Individual    
Name Robert Janssen  
Title M.D.,Chief Medical Officer and Senior Vice President  
Rule 10b5-1 Arrangement Terminated true  
Termination Date July 26, 2024  
Aggregate Available 311,535 311,535
August 2024 Arrangement [Member] | Robert Janssen [Member]    
Trading Arrangements, by Individual    
Name Robert Janssen  
Title M.D.,Chief Medical Officer and Senior Vice President  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date August 8, 2024  
Expiration Date November 13, 2025  
Arrangement Duration 462 days  
Aggregate Available 281,251 281,251