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Commitments and Contingencies - Narrative (Detail)
$ in Thousands, € in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Mar. 07, 2024
USD ($)
Oct. 31, 2023
USD ($)
Sep. 30, 2023
USD ($)
May 31, 2022
USD ($)
Sep. 30, 2021
USD ($)
Aug. 31, 2020
USD ($)
Nov. 30, 2009
USD ($)
Sep. 30, 2024
USD ($)
renewal_term
Mar. 31, 2024
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2024
USD ($)
renewal_term
Sep. 30, 2023
USD ($)
Sep. 30, 2024
EUR (€)
renewal_term
Feb. 22, 2024
ft²
Dec. 31, 2023
USD ($)
May 31, 2021
USD ($)
Loss Contingencies [Line Items]                                
Number of successive terms | renewal_term               2     2   2      
Renewal term               5 years     5 years   5 years      
Lease area | ft²                           75,662    
Termination of sublease agreement                 $ 3,500   $ 3,500          
Write-off of accrued balance $ 4,800                              
Collection of termination payment $ 1,300                              
Sublease (expense) income (Note 5)               $ 2,200   $ 2,000 $ 2,800 $ 5,600        
Percentage of excess rent paid                     0.50          
Cash paid for amounts included in the measurement of operating lease liabilities                     $ 5,700 $ 5,300        
Aggregate minimum commitment               700     700       $ 7,400  
Long-term debt, net of debt discount               1,939     1,939       2,802  
Symphony Dynamo Holdings LLC                                
Loss Contingencies [Line Items]                                
License arrangement contingent consideration percentage             50.00%                  
License arrangement upfront payment             $ 50,000                  
TriSalus                                
Loss Contingencies [Line Items]                                
Payment to holdings           $ 2,500                    
Payment received for pre-commercialization milestone     $ 1,000 $ 1,000 $ 1,000                      
TriSalus | Asset Purchase Agreement                                
Loss Contingencies [Line Items]                                
Payment made for pre-commercialization milestone   $ 500   $ 500 $ 500                      
Deutsche Bank Securities                                
Loss Contingencies [Line Items]                                
Letter of credit | €                         € 0.2      
Deutsche Bank Securities | Letter of credit                                
Loss Contingencies [Line Items]                                
Letter of credit | €                         € 0.2      
2.50% Convertible Senior Notes Due 2026                                
Loss Contingencies [Line Items]                                
Aggregate principal amount               225,500     225,500         $ 225,500
Long-term debt, net of debt discount               1,900     1,900          
HEPLISAV-B                                
Loss Contingencies [Line Items]                                
Non-cancelable purchase and other commitments               $ 34,000     $ 34,000       $ 43,400  
Minimum | Emeryville, California (Premises)                                
Loss Contingencies [Line Items]                                
Lease term               3 years     3 years   3 years      
Maximum | Emeryville, California (Premises)                                
Loss Contingencies [Line Items]                                
Lease term               12 years     12 years   12 years