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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Operating activities    
Net income (loss) $ 20,259 $ (6,608)
Adjustments to reconcile net income (loss) to net cash provided by operating activities:    
Depreciation and amortization 3,443 3,228
Amortization of right-of-use assets 2,538 2,090
Inventory write off 1,264 0
Sublease termination loss (Note 5) 4,765 0
Accretion of discounts on marketable securities (11,892) (11,313)
Stock-based compensation expense 39,615 31,283
Bad debt expense 0 12,313
Non-cash interest expense 2,272 2,246
Gain on sale of assets (Note 5) 0 (1,000)
Changes in operating assets and liabilities:    
Accounts and other receivables, net (30,744) 40,935
Inventories (10,376) 9,435
Prepaid manufacturing (6,893) 0
Prepaid expenses and other current assets (2,643) (4,650)
Other assets (878) 730
Accounts payable 2,023 (612)
Lease liabilities (3,220) (2,635)
Accrued and other liabilities 3,968 11,355
Net cash provided by operating activities 13,501 86,797
Investing activities    
Purchases of marketable securities (491,047) (484,040)
Proceeds from maturities and redemption of marketable securities 452,520 351,735
Purchases of property and equipment, net (2,874) (2,381)
Proceeds from sale of assets 0 1,000
Net cash used in investing activities (41,401) (133,686)
Financing activities    
Proceeds from exercise of stock options 3,925 4,339
Proceeds from Employee Stock Purchase Plan 1,760 1,535
Payments for taxes related to net share settlement of restricted stock units (8,827) (6,264)
Net cash used in financing activities (3,142) (390)
Effect of exchange rate changes on cash and cash equivalents, and restricted cash 98 (155)
Net decrease in cash and cash equivalents, and restricted cash (30,944) (47,434)
Cash and cash equivalents, and restricted cash at beginning of period 150,556 202,211
Cash and cash equivalents, and restricted cash at end of period 119,612 154,777
Supplemental disclosure of cash flow information    
Cash paid during the period for income taxes 4,577 1,413
Cash paid during the period for interest 2,819 2,819
Reclassification of contract asset from other current assets to other assets 0 71,307
Reclassification of CEPI accrual to CEPI accrual long-term 0 (60,337)
Advance Payments forgiven per CEPI-Bio E Assignment Agreement (Note 6) 0 (47,401)
Non-cash investing and financing activities:    
Purchases of property and equipment, not yet paid 762 704
Right-of-use assets obtained in exchange of operating lease liabilities $ 0 $ 1,332