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Summary of Significant Accounting Policies - Narrative (Detail) $ in Thousands | 12 Months Ended
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Dec. 31, 2024 USD ($) Segment reporting_unit | Dec. 31, 2023 USD ($) | Dec. 31, 2022 USD ($)
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |
Unrealized foreign currency translation (loss) gain | $ (2,400) | $ 1,100 | $ (1,800)
Currency transaction gain (loss) | $ 300 | $ (100) | 100
Number of operating segment | Segment | 1 |  |
Number of reporting units | reporting_unit | 1 |  |
Allowance for doubtful accounts | $ 12,300 |  |
Percentage of long lived assets | 26.00% | 31.00% |
Inventory write-off | $ 3,144 | $ 0 | 34,288
Goodwill impairment | 0 | 0 | $ 0
Dynavax |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |
Cumulative translation adjustment | $ (5,300) | (3,000) |
2.50% Convertible Senior Notes Due 2026 |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |
Debt interest rate | 2.50% |  |
HEPLISAV-B |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |
Inventory write-off | $ 0 | $ 0 |
HEPLISAV-B | Credit Concentration Risk | Trade Receivable | Three Customers |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |
Concentration risk, percentage | 97.00% | 81.00% |
Maximum |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |
Cash equivalents original maturity period | 3 months |  |
Percentage of long lived assets | 10.00% | 10.00% |
Expected period of payment to be received | 1 year |  |

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