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Income Taxes - Schedule of Component of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
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Deferred tax assets: |  |
Net operating loss carryforwards | $ 77,843 | $ 96,336
Research credit carryforwards | 32,516 | 34,940
Section 174 capitalization | 28,446 | 22,556
Lease liability | 6,914 | 8,868
Stock compensation | 11,479 | 10,572
Accruals and reserves | 21,579 | 15,808
Other | 563 | 348
Total deferred tax assets | 179,340 | 189,428
Less valuation allowance | (172,525) | (180,387)
Net deferred tax assets | 6,815 | 9,041
Deferred tax liabilities: |  |
Fixed assets | (2,101) | (2,667)
Operating lease right-of-use assets | (4,714) | (6,345)
Other | 0 | (29)
Total deferred tax liabilities | (6,815) | (9,041)
Net deferred tax assets | $ 0 | $ 0

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