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Summary of Significant Accounting Policies - Narrative (Detail)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
USD ($)
Segment
reporting_unit
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Unrealized foreign currency translation (loss) gain $ (2,400) $ 1,100 $ (1,800)
Currency transaction gain (loss) $ 300 $ (100) 100
Number of operating segment | Segment 1    
Number of reporting units | reporting_unit 1    
Allowance for doubtful accounts $ 12,300    
Percentage of long lived assets 26.00% 31.00%  
Inventory write-off $ 3,144 $ 0 34,288
Goodwill impairment 0 0 $ 0
Dynavax      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Cumulative translation adjustment $ (5,300) (3,000)  
2.50% Convertible Senior Notes Due 2026      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Debt interest rate 2.50%    
HEPLISAV-B      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Inventory write-off $ 0 $ 0  
HEPLISAV-B | Credit Concentration Risk | Trade Receivable | Three Customers      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Concentration risk, percentage 97.00% 81.00%  
Maximum      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Cash equivalents original maturity period 3 months    
Percentage of long lived assets 10.00% 10.00%  
Expected period of payment to be received 1 year