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Commitments and Contingencies - Narrative (Detail) $ in Millions	Sep. 30, 2025 USD ($) renewal_term
Loss Contingencies [Line Items]
Number of successive terms | renewal_term	2
Renewal term	5 years
HEPLISAV-B
Loss Contingencies [Line Items]
Non-cancelable purchase and other commitments | $	$ 83.2
Minimum | Emeryville, California (Premises)
Loss Contingencies [Line Items]
Lease term	3 years
Maximum | Emeryville, California (Premises)
Loss Contingencies [Line Items]
Lease term	12 years

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