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Equity Incentive Plans and Stock-Based Compensation (Tables)
3 Months Ended
Mar. 31, 2023
Share-Based Payment Arrangement [Abstract]  
Summary of Option Activity

The following table summarizes the stock option activity for the three months ended March 31, 2023:

 

 

 

Options

 

 

Weighted-
Average
Exercise
Price

 

 

Weighted-
Average
Remaining
Contractual
Term
(in years)

 

 

Aggregate
Intrinsic
Value
(in thousands)

 

Outstanding at December 31, 2022

 

 

6,690,492

 

 

$

4.27

 

 

 

 

 

 

 

Granted

 

 

1,796,570

 

 

$

6.00

 

 

 

 

 

 

 

Exercised

 

 

(16

)

 

$

1.60

 

 

 

 

 

 

 

Forfeited and cancelled

 

 

(12,647

)

 

$

5.37

 

 

 

 

 

 

 

Outstanding at March 31, 2023

 

 

8,474,399

 

 

$

4.64

 

 

 

8.7

 

 

$

12,929

 

Exercisable at March 31, 2023

 

 

1,755,709

 

 

$

3.92

 

 

 

5.7

 

 

$

5,938

 

 

Summary of Outstanding Shares of Potential Dilutive Securities Excluded from Computation of Diluted Net Loss per Share

The following outstanding shares of potentially dilutive securities were excluded from the computation of diluted net loss per share attributable to common stockholders for the periods presented because including them would have been anti-dilutive:

 

 

Three Months Ended March 31,

 

 

2023

 

 

2022

 

Options to purchase common stock

 

8,474,399

 

 

 

6,424,324

 

 Non-vested restricted stock units

 

485,942

 

 

 

217,730

 

Total

 

8,960,341

 

 

 

6,642,054

 

Summary of Fair Value of Stock Options Estimated Using Black-Scholes Merton Option Pricing Model Assumptions

The fair value of stock option awards to employees, executives, directors, and other service providers was estimated at the date of grant using the Black-Scholes-Merton option pricing model with the following assumptions:

 

 

 

Three Months Ended
March 31,

 

 

2023

 

2022

Risk-free interest rate

 

3.45%

 

1.47% - 1.70%

Expected volatility

 

87.68%

 

82.98% - 83.59%

Expected term (in years)

 

6.08

 

6.08

Expected dividend yield

 

0%

 

0%

Summary of Total Stock-based Compensation Expense

The table below summarizes the total stock-based compensation expense included in the Company’s statements of operations and comprehensive loss for the periods presented (in thousands):

 

 

Three Months Ended
March 31,

 

 

2023

 

 

2022

 

Research and development

$

1,475

 

 

$

1,568

 

General and administrative

 

2,139

 

 

 

2,377

 

Total stock-based compensation expense

$

3,614

 

 

$

3,945

 

Summary of Restricted Stock Unit Activity

The following table summarizes the restricted stock unit activity for the three months ended March 31, 2023:

 

 

Number of Shares

 

 

Weighted-
Average
Grant-Date
Fair Value

 

Outstanding at December 31, 2022

 

 

191,925

 

 

$

7.83

 

Granted

 

 

297,323

 

 

$

6.00

 

Vested

 

 

(1,662

)

 

$

7.97

 

Forfeited

 

 

(1,644

)

 

$

6.37

 

Outstanding at March 31, 2023

 

 

485,942

 

 

$

6.72