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License and Collaboration Agreements - License, Collaboration and Other Revenue (Detail) (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2014
Mar. 31, 2013
License And Collaboration Agreements [Line Items]    
License, collaboration, and other revenue $ 8,081 $ 6,476
Roche [Member] | PEGASYS and MIRCERA [Member]
   
License And Collaboration Agreements [Line Items]    
License, collaboration, and other revenue 3,197 2,625
Amgen, Inc. [Member] | Neulasta [Member]
   
License And Collaboration Agreements [Line Items]    
License, collaboration, and other revenue 1,250 1,285
Bayer Healthcare LLC [Member] | BAY41-6551 (Amikacin Inhale) [Member]
   
License And Collaboration Agreements [Line Items]    
License, collaboration, and other revenue 752 714
Baxter Healthcare [Member] | BAX 855 (Hemophilia) [Member]
   
License And Collaboration Agreements [Line Items]    
License, collaboration, and other revenue 337 700
Other [Member]
   
License And Collaboration Agreements [Line Items]    
License, collaboration, and other revenue $ 2,545 $ 1,152