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License and Collaboration Agreements - License, Collaboration and Other Revenue (Detail) (USD $) In Thousands, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
License And Collaboration Agreements [Line Items]
License, collaboration and other revenue	$ 17,785	$ 19,359	$ 25,866	$ 25,835
Bayer Healthcare LLC [Member] | BAY41-6551 (Amikacin Inhale) [Member]
License And Collaboration Agreements [Line Items]
License, collaboration and other revenue	2,393	13,111	3,146	13,825
Roche [Member] | PEGASYS and MIRCERA [Member]
License And Collaboration Agreements [Line Items]
License, collaboration and other revenue	3,219	2,625	6,415	5,250
Amgen, Inc. [Member] | Neulasta [Member]
License And Collaboration Agreements [Line Items]
License, collaboration and other revenue	1,250	1,250	2,500	2,535
Baxter Healthcare [Member] | BAX 855 (Hemophilia) [Member]
License And Collaboration Agreements [Line Items]
License, collaboration and other revenue	669	597	1,006	1,297
Other [Member]
License And Collaboration Agreements [Line Items]
License, collaboration and other revenue	$ 10,254	$ 1,776	$ 12,799	$ 2,928

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- Definition

Revenue earned during the period relating to consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Revenue may contain one or more of the following elements: upfront fees, contract research, milestone payments, manufacturing and supply, royalties, and license fees.

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