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Stock-Based Compensation - Stock-Based Compensation Expense (Detail) (USD $) In Thousands, unless otherwise specified | 12 Months Ended
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Dec. 31, 2014 | Dec. 31, 2013 | Dec. 31, 2012
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] |  |  |
Total stock-based compensation | $ 17,017 us-gaap_ShareBasedCompensation | $ 17,708 us-gaap_ShareBasedCompensation | $ 16,199 us-gaap_ShareBasedCompensation
Cost of Goods Sold [Member] |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] |  |  |
Total stock-based compensation | 1,161 us-gaap_ShareBasedCompensation / us-gaap_IncomeStatementLocationAxis = us-gaap_CostOfSalesMember | 1,297 us-gaap_ShareBasedCompensation / us-gaap_IncomeStatementLocationAxis = us-gaap_CostOfSalesMember | 1,496 us-gaap_ShareBasedCompensation / us-gaap_IncomeStatementLocationAxis = us-gaap_CostOfSalesMember
Research and Development [Member] |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] |  |  |
Total stock-based compensation | 7,528 us-gaap_ShareBasedCompensation / us-gaap_IncomeStatementLocationAxis = nktr_ResearchAndDevelopmentMember | 7,910 us-gaap_ShareBasedCompensation / us-gaap_IncomeStatementLocationAxis = nktr_ResearchAndDevelopmentMember | 7,082 us-gaap_ShareBasedCompensation / us-gaap_IncomeStatementLocationAxis = nktr_ResearchAndDevelopmentMember
General and Administrative [Member] |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] |  |  |
Total stock-based compensation | $ 8,328 us-gaap_ShareBasedCompensation / us-gaap_IncomeStatementLocationAxis = us-gaap_GeneralAndAdministrativeExpenseMember | $ 8,501 us-gaap_ShareBasedCompensation / us-gaap_IncomeStatementLocationAxis = us-gaap_GeneralAndAdministrativeExpenseMember | $ 7,621 us-gaap_ShareBasedCompensation / us-gaap_IncomeStatementLocationAxis = us-gaap_GeneralAndAdministrativeExpenseMember

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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
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- Details
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