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Selected Quarterly Financial Data (Tables) | 12 Months Ended
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Dec. 31, 2014
Quarterly Financial Information Disclosure [Abstract] |
Quarterly Financial Data | The following table sets forth certain unaudited quarterly financial data. In our opinion, the unaudited information set forth below has been prepared on the same basis as the audited information and includes all adjustments necessary to present fairly the information set forth herein. All data is in thousands except per share information.
|  | Fiscal Year 2014 |  |  | Fiscal Year 2013 |
|  | Q1 |  |  | Q2 |  |  | Q3 |  |  | Q4 |  |  | Q1 |  |  | Q2 |  |  | Q3 |  |  | Q4 |
Product sales |  | $ | 5,795 |  |  | $ | 5,802 |  |  | $ | 6,096 |  |  | $ | 7,460 |  |  | $ | 11,810 |  |  | $ | 10,324 |  |  | $ | 14,672 |  |  | $ | 8,040 |
Total revenue |  | $ | 19,771 |  |  | $ | 28,513 |  |  | $ | 132,871 |  |  | $ | 19,551 |  |  | $ | 23,004 |  |  | $ | 33,862 |  |  | $ | 60,909 |  |  | $ | 31,146 |
Cost of goods sold |  | $ | 7,907 |  |  | $ | 5,108 |  |  | $ | 9,220 |  |  | $ | 6,298 |  |  | $ | 11,661 |  |  | $ | 5,011 |  |  | $ | 12,877 |  |  | $ | 8,960 |
Research and development expenses |  | $ | 38,338 |  |  | $ | 36,702 |  |  | $ | 34,200 |  |  | $ | 38,494 |  |  | $ | 45,618 |  |  | $ | 52,230 |  |  | $ | 43,914 |  |  | $ | 48,248 |
Operating income (loss) |  | $ | (36,402 | ) |  | $ | (22,916 | ) |  | $ | 80,321 |  |  | $ | (37,488 | ) |  | $ | (45,106 | ) |  | $ | (32,605 | ) |  | $ | (6,525 | ) |  | $ | (35,894 | )
Net income (loss) |  | $ | (46,201 | ) |  | $ | (32,637 | ) |  | $ | 70,605 |  |  | $ | (45,683 | ) |  | $ | (55,063 | ) |  | $ | (42,748 | ) |  | $ | (16,543 | ) |  | $ | (47,659 | )
Net income (loss) per share(1) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Basic |  | $ | (0.37 | ) |  | $ | (0.26 | ) |  | $ | 0.55 |  |  | $ | (0.35 | ) |  | $ | (0.48 | ) |  | $ | (0.37 | ) |  | $ | (0.14 | ) |  | $ | (0.41 | )
Diluted |  | $ | (0.37 | ) |  | $ | (0.26 | ) |  | $ | 0.53 |  |  | $ | (0.35 | ) |  | $ | (0.48 | ) |  | $ | (0.37 | ) |  | $ | (0.14 | ) |  | $ | (0.41 | )
(1) | Quarterly loss per share amounts may not total to the year-to-date loss per share due to rounding.

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- Definition Tabular disclosure of the quarterly financial data in the annual financial statements. The disclosure includes financial information for each fiscal quarter for the current and previous year, including revenues, gross profit, income (loss) before extraordinary items and cumulative effect of a change in accounting principle and earnings per share data. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a)-(j) -URI http://asc.fasb.org/extlink&oid=35737889&loc=d3e1280-108306 + Details
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