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v2.4.1.9

Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified | 12 Months Ended
--- | ---
Dec. 31, 2014 | Dec. 31, 2013 | Dec. 31, 2012
Cash flows from operating activities: |  |  |
Net loss | $ (53,916)us-gaap_NetIncomeLoss | $ (162,013)us-gaap_NetIncomeLoss | $ (171,855)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Non-cash royalty revenue related to sale of future royalties | (21,937)nktr_NonCashRoyaltyRevenueRelatedToSaleOfFutureRoyalties | (22,055)nktr_NonCashRoyaltyRevenueRelatedToSaleOfFutureRoyalties | (10,791)nktr_NonCashRoyaltyRevenueRelatedToSaleOfFutureRoyalties
Non-cash interest expense on liability related to sale of future royalties | 20,888 nktr_NonCashInterestExpenseRelatedToSaleOfRoyalties | 22,309 nktr_NonCashInterestExpenseRelatedToSaleOfRoyalties | 18,057 nktr_NonCashInterestExpenseRelatedToSaleOfRoyalties
Stock-based compensation | 17,017 us-gaap_AllocatedShareBasedCompensationExpense | 17,708 us-gaap_AllocatedShareBasedCompensationExpense | 16,199 us-gaap_AllocatedShareBasedCompensationExpense
Depreciation and amortization | 12,927 us-gaap_DepreciationAndAmortization | 14,275 us-gaap_DepreciationAndAmortization | 14,508 us-gaap_DepreciationAndAmortization
Other non-cash transactions | (560)us-gaap_OtherNoncashIncomeExpense | 664 us-gaap_OtherNoncashIncomeExpense | 2,520 us-gaap_OtherNoncashIncomeExpense
Changes in assets and liabilities: |  |  |
Accounts receivable, net | (1,378)us-gaap_IncreaseDecreaseInAccountsReceivable | 3,576 us-gaap_IncreaseDecreaseInAccountsReceivable | (867)us-gaap_IncreaseDecreaseInAccountsReceivable
Inventory | 500 us-gaap_IncreaseDecreaseInInventories | 4,817 us-gaap_IncreaseDecreaseInInventories | (5,613)us-gaap_IncreaseDecreaseInInventories
Other assets | (3,294)us-gaap_IncreaseDecreaseInOtherOperatingAssets | 6,423 us-gaap_IncreaseDecreaseInOtherOperatingAssets | 6,031 us-gaap_IncreaseDecreaseInOtherOperatingAssets
Accounts payable | (6,359)us-gaap_IncreaseDecreaseInAccountsPayable | 6,199 us-gaap_IncreaseDecreaseInAccountsPayable | (122)us-gaap_IncreaseDecreaseInAccountsPayable
Accrued compensation | (8,505)us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities | 5,481 us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities | (4,034)us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities
Accrued expenses | 273 us-gaap_IncreaseDecreaseInAccruedLiabilities | (1,915)us-gaap_IncreaseDecreaseInAccruedLiabilities | 1,495 us-gaap_IncreaseDecreaseInAccruedLiabilities
Accrued clinical trial expenses | (9,197)nktr_IncreaseDecreaseInAccruedClinicalTrialExpenses | (595)nktr_IncreaseDecreaseInAccruedClinicalTrialExpenses | 5,547 nktr_IncreaseDecreaseInAccruedClinicalTrialExpenses
Interest payable |  | (166)us-gaap_IncreaseDecreaseInInterestPayableNet | 5,278 us-gaap_IncreaseDecreaseInInterestPayableNet
Deferred revenue | (4,664)us-gaap_IncreaseDecreaseInDeferredRevenue | (12,399)us-gaap_IncreaseDecreaseInDeferredRevenue | (9,384)us-gaap_IncreaseDecreaseInDeferredRevenue
Liability related to receipt of refundable milestone payment | (70,000)nktr_IncreaseDecreaseInMilestonePaymentLiabilities | 70,000 nktr_IncreaseDecreaseInMilestonePaymentLiabilities |
Other liabilities | (13,801)us-gaap_IncreaseDecreaseInOtherOperatingLiabilities | 9,164 us-gaap_IncreaseDecreaseInOtherOperatingLiabilities | 3,275 us-gaap_IncreaseDecreaseInOtherOperatingLiabilities
Net cash used in operating activities | (142,006)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (38,527)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (129,756)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Cash flows from investing activities: |  |  |
Maturities of investments | 247,995 us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities | 319,181 us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities | 307,887 us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities
Purchases of investments | (297,251)us-gaap_PaymentsToAcquireAvailableForSaleSecurities | (268,068)us-gaap_PaymentsToAcquireAvailableForSaleSecurities | (164,662)us-gaap_PaymentsToAcquireAvailableForSaleSecurities
Sales of investments | 21,661 us-gaap_ProceedsFromSaleOfAvailableForSaleSecurities | 2,887 us-gaap_ProceedsFromSaleOfAvailableForSaleSecurities | 5,378 us-gaap_ProceedsFromSaleOfAvailableForSaleSecurities
Restricted cash |  |  | (25,000)us-gaap_IncreaseDecreaseInRestrictedCash
Purchases of property, plant and equipment | (9,976)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (4,091)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (10,583)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Net cash (used in) provided by investing activities | (37,571)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | 49,909 us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | 113,020 us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Cash flows from financing activities: |  |  |
Payment of capital lease obligations | (3,536)us-gaap_RepaymentsOfLongTermCapitalLeaseObligations | (2,992)us-gaap_RepaymentsOfLongTermCapitalLeaseObligations | (2,437)us-gaap_RepaymentsOfLongTermCapitalLeaseObligations
Issuance of common stock, net of issuance costs | 116,536 nktr_ProceedsFromIssuanceOfCommonStockNetOfIssuanceCosts |  |
(Repayment of) proceeds from sale of future royalties, net of $4.4 million of transaction costs in 2012 | (7,000)nktr_RepaymentOfAndProceedsFromSaleOfFutureRoyaltiesNetOfTransactionCosts | (3,000)nktr_RepaymentOfAndProceedsFromSaleOfFutureRoyaltiesNetOfTransactionCosts | 119,588 nktr_RepaymentOfAndProceedsFromSaleOfFutureRoyaltiesNetOfTransactionCosts
Proceeds from issuance of senior secured notes, net of $4.5 million of issuance costs |  |  | 77,940 us-gaap_ProceedsFromIssuanceOfSecuredDebt
Repayment of convertible subordinated notes |  |  | (172,407)us-gaap_RepaymentsOfSubordinatedDebt
Proceeds from shares issued under equity compensation plans | 46,984 us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans | 8,208 us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans | 4,117 us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans
Net cash provided by financing activities | 152,984 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 2,216 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 26,801 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Effect of exchange rates on cash and cash equivalents | (109)us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents | 32 us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents | 60 us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents
Net (decrease) increase in cash and cash equivalents | (26,702)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease | 13,630 us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease | 10,125 us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents at beginning of year | 39,067 us-gaap_CashAndCashEquivalentsAtCarryingValue | 25,437 us-gaap_CashAndCashEquivalentsAtCarryingValue | 15,312 us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents at end of year | 12,365 us-gaap_CashAndCashEquivalentsAtCarryingValue | 39,067 us-gaap_CashAndCashEquivalentsAtCarryingValue | 25,437 us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosure of cash flow information: |  |  |
Cash paid for interest | 17,445 us-gaap_InterestPaid | 17,590 us-gaap_InterestPaid | 9,620 us-gaap_InterestPaid
Cash paid for income taxes | 964 us-gaap_IncomeTaxesPaidNet | 1,014 us-gaap_IncomeTaxesPaidNet | 1,021 us-gaap_IncomeTaxesPaidNet
Supplemental schedule of non-cash investing and financing activities: |  |  |
Property and equipment acquired through capital leases and other financing | 5,231 nktr_PropertyAndEquipmentAcquiredThroughCapitalLeasesAndOtherFinancing | 2,000 nktr_PropertyAndEquipmentAcquiredThroughCapitalLeasesAndOtherFinancing |
Retirement of convertible subordinated notes in exchange for senior secured notes |  |  | $ 42,548 us-gaap_DebtConversionOriginalDebtAmount1

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- Definition Amount of cash inflow (outflow) from operating activities, excluding discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3521-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 25 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3536-108585 + Details
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Other Comprehensive Income -URI http://asc.fasb.org/extlink&oid=6519514 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Net Income -URI http://asc.fasb.org/extlink&oid=6518256 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 225 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-04.19) -URI http://asc.fasb.org/extlink&oid=6879464&loc=d3e573970-122913 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.18) -URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688 Reference 7: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 225 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-04.22) -URI http://asc.fasb.org/extlink&oid=6879464&loc=d3e573970-122913 Reference 8: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 03 -Paragraph 19 -Article 5 Reference 9: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 04 -Paragraph 20 -Article 9 + Details
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