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Consolidated Statements of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Revenue:    
Product sales and royalty revenue $ 8,099nktr_ProductSalesAndRoyalties $ 5,917nktr_ProductSalesAndRoyalties
Non-cash royalty revenue related to sale of future royalties 3,962nktr_NonCashRoyaltyRevenueRelatedToSaleOfFutureRoyalties 5,773nktr_NonCashRoyaltyRevenueRelatedToSaleOfFutureRoyalties
License, collaboration and other revenue 96,740nktr_LicenseCollaborationOtherRevenue 8,081nktr_LicenseCollaborationOtherRevenue
Total revenue 108,801us-gaap_Revenues 19,771us-gaap_Revenues
Operating costs and expenses:    
Cost of goods sold 8,444us-gaap_CostOfGoodsSold 7,907us-gaap_CostOfGoodsSold
Research and development 47,011us-gaap_ResearchAndDevelopmentExpense 38,338us-gaap_ResearchAndDevelopmentExpense
General and administrative 10,303us-gaap_GeneralAndAdministrativeExpense 9,928us-gaap_GeneralAndAdministrativeExpense
Total operating costs and expenses 65,758us-gaap_CostsAndExpenses 56,173us-gaap_CostsAndExpenses
Income (loss) from operations 43,043us-gaap_OperatingIncomeLoss (36,402)us-gaap_OperatingIncomeLoss
Non-operating income (expense):    
Interest expense (4,171)us-gaap_InterestExpense (4,533)us-gaap_InterestExpense
Non-cash interest expense on liability related to sale of future royalties (5,050)nktr_NonCashInterestExpenseRelatedToSaleOfRoyalties (5,387)nktr_NonCashInterestExpenseRelatedToSaleOfRoyalties
Interest income and other income (expense), net 211us-gaap_OtherNonoperatingIncomeExpense 312us-gaap_OtherNonoperatingIncomeExpense
Total non-operating expense, net (9,010)us-gaap_NonoperatingIncomeExpense (9,608)us-gaap_NonoperatingIncomeExpense
Income (loss) before provision for income taxes 34,033us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest (46,010)us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
Provision for income taxes 213us-gaap_IncomeTaxExpenseBenefit 191us-gaap_IncomeTaxExpenseBenefit
Net income (loss) $ 33,820us-gaap_NetIncomeLoss $ (46,201)us-gaap_NetIncomeLoss
Net income (loss) per share:    
Basic $ 0.26us-gaap_EarningsPerShareBasic $ (0.37)us-gaap_EarningsPerShareBasic
Diluted $ 0.25us-gaap_EarningsPerShareDiluted $ (0.37)us-gaap_EarningsPerShareDiluted
Weighted average shares outstanding used in computing net income (loss) per share    
Basic 131,359us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 123,543us-gaap_WeightedAverageNumberOfSharesOutstandingBasic
Diluted 135,667us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 123,543us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding