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Liability Related to Sale of Future Royalties - Additional Information (Detail) - USD ($)
$ in Thousands
 1 Months Ended 3 Months Ended 6 Months Ended
Feb. 24, 2012
Mar. 31, 2014
Mar. 31, 2013
Jun. 30, 2015
Jun. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Liability Related to Sale of Future Royalties [Line Items]              
Non-cash royalty revenue related to sale of future royalties       $ 4,740 $ 4,837 $ 8,702 $ 10,610
Annual interest rate           17.00%  
Royalty agreement contingent payment description           As a result of worldwide net sales of MIRCERA® for the 12 month periods ended December 31, 2013 and 2012 not reaching certain minimum thresholds.  
Milestone Scenario One [Member]              
Liability Related to Sale of Future Royalties [Line Items]              
Payment made for milestone not achieved year one     $ 3,000        
Milestone Scenario Two [Member]              
Liability Related to Sale of Future Royalties [Line Items]              
Payment made for milestone not achieved year two   $ 7,000          
Purchase and Sale Agreement with RPI [Member]              
Liability Related to Sale of Future Royalties [Line Items]              
Proceeds from sale of royalty rights $ 124,000