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Property, Plant and Equipment (Tables) | 12 Months Ended
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Dec. 31, 2015
Property Plant And Equipment [Abstract] |
Property, Plant and Equipment | Property, plant and equipment consists of the following (in thousands):
|  | December 31, |
|  | 2015 |  |  | 2014 |
Building and leasehold improvements |  | $ | 77,665 |  |  | $ | 72,228 |
Laboratory equipment |  |  | 27,309 |  |  |  | 26,975 |
Manufacturing equipment |  |  | 35,631 |  |  |  | 25,212 |
Furniture, fixtures and other equipment |  |  | 24,987 |  |  |  | 23,451 |
Depreciable property, plant and equipment at cost |  |  | 165,592 |  |  |  | 147,866 |
Less: accumulated depreciation |  |  | (102,712 | ) |  |  | (93,807 | )
Depreciable property, plant and equipment, net |  |  | 62,880 |  |  |  | 54,059 |
Construction-in-progress |  |  | 8,456 |  |  |  | 16,309 |
Property, plant and equipment, net |  | $ | 71,336 |  |  | $ | 70,368 |

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- Definition Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.13) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 13 -Subparagraph b -Article 5 + Details
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