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Leases - Additional Information (Detail) $ in Millions | 12 Months Ended |
--- | --- | ---
Dec. 31, 2016 USD ($) | Dec. 31, 2015 USD ($) | Dec. 31, 2014 USD ($) | Sep. 30, 2009 ft²
Leases [Line Items] |  |  |  |
Book value of assets, gross | $ 8.2 | $ 5.1 |  |
Net book value of assets | $ 7.4 | 3.2 |  |
San Carlos facility capital leases, end date | Oct. 05, 2016 |  |  |
Operating Sublease term commenced start date | 2010-08 |  |  |
Operating Sublease term commenced period | 114 months |  |  |
Operating Sublease term commenced end date | Jan. 31, 2020 |  |  |
Rent expense | $ 3.2 | 3.2 | $ 3.2 |
Deferred rent | $ 6.6 | $ 8.5 |  |
Pfizer, Inc. [Member] |  |  |  |
Leases [Line Items] |  |  |  |
Operating sublease | ft² |  |  |  | 126,285

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- Definition Amount before accumulated depreciation of leased physical assets used in the normal conduct of business to produce goods and services. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 30 -Section 45 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6455314&loc=d3e45014-112735 + Details
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- Definition The total gross amount less the charge for the use of the long-lived depreciable assets subject to a lease meeting the criteria for capitalization. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6455398&loc=d3e45280-112737 + Details
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- Definition For a classified balance sheet, the cumulative difference between the rental income or payments required by a lease agreement and the rental income or expense recognized on a straight-line basis, or other systematic and rational basis more representative of the time pattern in which use or benefit is granted or derived from the leased property, expected to be recognized in income or expense, by the lessor or lessee, respectively, more than one year after the balance sheet date. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.26(c)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 20 -Section 25 -Paragraph 2 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=7501430&loc=d3e39927-112707 + Details
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