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Commitments and Contingencies - Additional Information (Detail) |  |  | 1 Months Ended | 9 Months Ended |  |
--- | --- | --- | --- | --- | --- | ---
Jun. 30, 2017 USD ($) | Jun. 26, 2017 USD ($) | Aug. 31, 2017 ft² yr | Jun. 30, 2017 USD ($) | Sep. 30, 2017 USD ($) | Dec. 31, 2016 USD ($) | Aug. 14, 2015 USD ($)
Indemnification Obligation [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Litigation matters, liabilities |  |  |  |  | $ 0 | $ 0 |
Cross-License Agreement [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Total payments due related to license agreement amendment |  | $ 7,000,000 |  |  |  |  |
Payment made related to license agreement amendment |  |  |  | $ 3,500,000 |  |  |
Litigation matters, prepayment of royalty obligations | $ 2,300,000 |  |  |  |  |  |
Litigation matters, liabilities |  |  |  |  |  | $ 0 |
Cross-License Agreement [Member] | Cost of Goods Sold [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Accrued royalties |  |  |  |  | 1,400,000 |  |
Cross-License Agreement [Member] | General and Administrative Expense [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Accrued expense related to license agreement amendment |  |  |  |  | 3,300,000 |  |
Cross-License Agreement [Member] | Other Current Liabilities [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Liability related to license agreement amendment |  |  |  |  | 3,500,000 |  |
Cross-License Agreement [Member] | Other Current Assets [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Unamortized prepaid royalty |  |  |  |  | $ 1,500,000 |  |
Enzon Litigation [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Damage claim for alleged unpaid licenses |  |  |  |  |  |  | $ 1,500,000
Enzon Litigation [Member] | Cross-License Agreement [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Litigation matters, dismissal date |  |  |  |  | Jun. 30, 2017 |  |
ARE-San Francisco No. 19, LLC [Member] |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |
Lease space | ft² |  |  | 128,793 |  |  |  |
Extended lease term start year |  |  | 2020 |  |  |  |
Lease expiration year |  |  | 2030 |  |  |  |
Lease description option to extend |  |  | The term of the Lease commenced on September 1, 2017, and will expire January 31, 2030, subject to our right to extend the term of the Lease for two consecutive five-year periods. |  |  |  |
Number of consecutive 5 year terms to extend lease | yr |  |  | 2 |  |  |  |
Lease extension term |  |  | 5 years |  |  |  |
Lease commencement date |  |  |  |  | Sep. 01, 2017 |  |
Lease expiration date |  |  |  |  | Jan. 31, 2030 |  |
Additional lease space | ft² |  |  | 24,000 |  |  |  |

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