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Commitments and Contingencies - Additional Information (Detail)			1 Months Ended		9 Months Ended
	Jun. 30, 2017 USD ($)	Jun. 26, 2017 USD ($)	Aug. 31, 2017 ft² yr	Jun. 30, 2017 USD ($)	Sep. 30, 2017 USD ($)	Dec. 31, 2016 USD ($)	Aug. 14, 2015 USD ($)
Indemnification Obligation [Member]
Loss Contingencies [Line Items]
Litigation matters, liabilities					$ 0	$ 0
Cross-License Agreement [Member]
Loss Contingencies [Line Items]
Total payments due related to license agreement amendment		$ 7,000,000
Payment made related to license agreement amendment				$ 3,500,000
Litigation matters, prepayment of royalty obligations	$ 2,300,000
Litigation matters, liabilities						$ 0
Cross-License Agreement [Member] | Cost of Goods Sold [Member]
Loss Contingencies [Line Items]
Accrued royalties					1,400,000
Cross-License Agreement [Member] | General and Administrative Expense [Member]
Loss Contingencies [Line Items]
Accrued expense related to license agreement amendment					3,300,000
Cross-License Agreement [Member] | Other Current Liabilities [Member]
Loss Contingencies [Line Items]
Liability related to license agreement amendment					3,500,000
Cross-License Agreement [Member] | Other Current Assets [Member]
Loss Contingencies [Line Items]
Unamortized prepaid royalty					$ 1,500,000
Enzon Litigation [Member]
Loss Contingencies [Line Items]
Damage claim for alleged unpaid licenses							$ 1,500,000
Enzon Litigation [Member] | Cross-License Agreement [Member]
Loss Contingencies [Line Items]
Litigation matters, dismissal date					Jun. 30, 2017
ARE-San Francisco No. 19, LLC [Member]
Loss Contingencies [Line Items]
Lease space | ft²			128,793
Extended lease term start year			2020
Lease expiration year			2030
Lease description option to extend			The term of the Lease commenced on September 1, 2017, and will expire January 31, 2030, subject to our right to extend the term of the Lease for two consecutive five-year periods.
Number of consecutive 5 year terms to extend lease | yr			2
Lease extension term			5 years
Lease commencement date					Sep. 01, 2017
Lease expiration date					Jan. 31, 2030
Additional lease space | ft²			24,000

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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