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Segment Reporting - Additional Information (Detail) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2017 USD ($) Segment | Dec. 31, 2016 USD ($) | Dec. 31, 2015
Segment Reporting Information [Line Items] |  |  |
Number of operating business segment | Segment | 1 |  |
Property, plant and equipment, net | $ 47,463 | $ 65,601 |
United States [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Property, plant and equipment, net | $ 41,700 | $ 48,800 |
Percentage of net book value of property and equipment | 88.00% | 74.00% |
India [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Property, plant and equipment, net | $ 5,800 | $ 5,600 |
Percentage of net book value of property and equipment | 12.00% | 9.00% |
Germany and Netherlands [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Property, plant and equipment, net |  | $ 10,400 |
Percentage of net book value of property and equipment |  | 16.00% |
Other Countries [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Property, plant and equipment, net |  | $ 800 |
Percentage of net book value of property and equipment |  | 1.00% |
Revenue [Member] | Eli Lilly & Co [Member] | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from clients | 42.00% |  |
Revenue [Member] | UCB [Member] | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from clients | 12.00% | 21.00% | 13.00%
Revenue [Member] | AstraZeneca [Member] | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from clients |  | 29.00% | 57.00%
Revenue [Member] | Ophthotech Corporation [Member] | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from clients |  | 19.00% |
Revenue [Member] | Roche [Member] | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from clients |  | 11.00% |

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- Definition For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 275 -SubTopic 10 -Section 50 -Paragraph 18 -URI http://asc.fasb.org/extlink&oid=84177426&loc=d3e6351-108592 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 825 -SubTopic 10 -Section 50 -Paragraph 20 -URI http://asc.fasb.org/extlink&oid=77997519&loc=d3e13531-108611 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 275 -SubTopic 10 -Section 50 -Paragraph 20 -URI http://asc.fasb.org/extlink&oid=84177426&loc=d3e6404-108592 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 825 -SubTopic 10 -Section 50 -Paragraph 21 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=77997519&loc=d3e13537-108611 + Details
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