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Segment Reporting - Additional Information (Detail) $ in Thousands	12 Months Ended
	Dec. 31, 2017 USD ($) Segment	Dec. 31, 2016 USD ($)	Dec. 31, 2015
Segment Reporting Information [Line Items]
Number of operating business segment | Segment	1
Property, plant and equipment, net	$ 47,463	$ 65,601
United States [Member]
Segment Reporting Information [Line Items]
Property, plant and equipment, net	$ 41,700	$ 48,800
Percentage of net book value of property and equipment	88.00%	74.00%
India [Member]
Segment Reporting Information [Line Items]
Property, plant and equipment, net	$ 5,800	$ 5,600
Percentage of net book value of property and equipment	12.00%	9.00%
Germany and Netherlands [Member]
Segment Reporting Information [Line Items]
Property, plant and equipment, net		$ 10,400
Percentage of net book value of property and equipment		16.00%
Other Countries [Member]
Segment Reporting Information [Line Items]
Property, plant and equipment, net		$ 800
Percentage of net book value of property and equipment		1.00%
Revenue [Member] | Eli Lilly & Co [Member] | Customer Concentration Risk [Member]
Segment Reporting Information [Line Items]
Percentage revenue from clients	42.00%
Revenue [Member] | UCB [Member] | Customer Concentration Risk [Member]
Segment Reporting Information [Line Items]
Percentage revenue from clients	12.00%	21.00%	13.00%
Revenue [Member] | AstraZeneca [Member] | Customer Concentration Risk [Member]
Segment Reporting Information [Line Items]
Percentage revenue from clients		29.00%	57.00%
Revenue [Member] | Ophthotech Corporation [Member] | Customer Concentration Risk [Member]
Segment Reporting Information [Line Items]
Percentage revenue from clients		19.00%
Revenue [Member] | Roche [Member] | Customer Concentration Risk [Member]
Segment Reporting Information [Line Items]
Percentage revenue from clients		11.00%

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Percentage Of Property Plant Equipment Net In Assets

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For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 275
-SubTopic 10
-Section 50
-Paragraph 18
-URI http://asc.fasb.org/extlink&oid=84177426&loc=d3e6351-108592

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Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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