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Organization and Summary of Significant Accounting Policies - Additional Information (Detail) $ in Thousands	3 Months Ended			12 Months Ended
	Mar. 31, 2018 USD ($) Segment	Dec. 31, 2017 USD ($)	Mar. 31, 2017 USD ($)	Dec. 31, 2017 USD ($)	Jan. 01, 2018 USD ($)
Organization And Summary Of Significant Accounting Policies [Line Items]
Cash and investments in marketable securities	$ 333,816	$ 353,220		$ 353,220
Senior secured notes	$ 250,000
Senior secured notes, maturity date	Oct. 05, 2020
Number of operating business segment | Segment	1
Royalty revenue	$ 11,076		$ 7,217
Statutory income tax rate	21.00%			35.00%
India
Organization And Summary Of Significant Accounting Policies [Line Items]
Effective income tax rate – India	31.00%		35.00%
ASC 606 [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Revenue recognized from contracts with customers	$ 38,000
Adjustment to retained earnings					$ 12,700
ASC 606 [Member] | MOVANTIK and ADYNOVATE [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Royalty revenue	11,100	$ 9,600
ASC 606 [Member] | Recognition of Royalties [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Adjustment to retained earnings					10,700
ASC 606 [Member] | Recognition of Royalties [Member] | MOVANTIK and ADYNOVATE [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Adjustment to retained earnings					10,700
ASC 606 [Member] | Reduction of Deferred Revenue [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Adjustment to retained earnings					$ (2,000)
Calculated under Revenue Guidance in Effect before Topic 606 [Member] | ASC 606 [Member]
Organization And Summary Of Significant Accounting Policies [Line Items]
Revenue recognized from contracts with customers	37,900
Royalty revenue	$ 10,744

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