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Segment Reporting - Additional Information (Detail) $ in Thousands | 12 Months Ended
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Dec. 31, 2018 USD ($) Segment | Dec. 31, 2017 USD ($) | Dec. 31, 2016
Segment Reporting Information [Line Items] |  |  |
Number of operating business segment | Segment | 1 |  |
Property, plant and equipment, net | $ 48,851 | $ 47,463 |
United States [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Property, plant and equipment, net | $ 42,900 | $ 41,700 |
Percentage of net book value of property and equipment | 88.00% | 88.00% |
India [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Property, plant and equipment, net | $ 5,900 | $ 5,800 |
Percentage of net book value of property and equipment | 12.00% | 12.00% |
Revenue [Member] | BMS | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from customers | 89.00% |  |
Revenue [Member] | Eli Lilly & Co [Member] | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from customers |  | 42.00% |
Revenue [Member] | UCB [Member] | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from customers |  | 12.00% | 21.00%
Revenue [Member] | AstraZeneca [Member] | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from customers |  |  | 29.00%
Revenue [Member] | Ophthotech Corporation [Member] | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from customers |  |  | 19.00%
Revenue [Member] | Roche [Member] | Customer Concentration Risk [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Percentage revenue from customers |  |  | 11.00%

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