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License and Collaboration Agreements - Changes in Deferred Revenue Balance from Collaboration Agreements (Detail) $ in Thousands | 3 Months Ended
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Mar. 31, 2019 USD ($)
Organization Consolidation And Presentation Of Financial Statements [Abstract] |
Deferred revenue, Beginning balance | $ 24,636
Recognition of previously unearned revenue | (4,204)
Deferred revenue, Ending balance | $ 20,432

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