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Stock-Based Compensation | 6 Months Ended
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Jun. 30, 2019
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] |
Stock-Based Compensation | Stock-Based Compensation Total stock-based compensation expense was recognized in our Condensed Consolidated Statements of Operations as follows (in thousands):
| Three months ended June 30, |  | Six months ended June 30,
| 2019 |  | 2018 |  | 2019 |  | 2018
Cost of goods sold | $ | 1,086 |  |  | $ | 1,163 |  |  | $ | 2,089 |  |  | $ | 2,294 |
Research and development | 15,430 |  |  | 12,990 |  |  | 31,870 |  |  | 25,084 |
General and administrative | 8,006 |  |  | 6,506 |  |  | 15,948 |  |  | 13,230 |
Total stock-based compensation | $ | 24,522 |  |  | $ | 20,659 |  |  | $ | 49,907 |  |  | $ | 40,608 |
During the three months ended June 30, 2019 and 2018, we granted 95,000 and 528,975 stock options, respectively, and these options had a weighted average grant-date fair value of $17.00 per share and $44.32 per share, respectively. During the six months ended June 30, 2019 and 2018, we granted 115,455 and 738,675 stock options, respectively, and these options had a weighted average grant-date fair value of $18.51 per share and $41.53 per share, respectively. During the three months ended June 30, 2019 and 2018, we granted 262,750 and 396,240 RSUs, respectively. During the six months ended June 30, 2019 and 2018, we granted 395,570 and 406,240 RSUs, respectively, and these RSUs had a weighted average grant-date fair value of $34.85 per share and $53.44 per share, respectively. As a result of stock issuances under our equity compensation plans, during the three months ended June 30, 2019 and 2018, we issued 738,538 and 1,750,908 shares of our common stock, respectively, and during the six months ended June 30, 2019 and 2018, we issued 1,436,538 and 4,605,724 shares of our common stock, respectively.

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- Definition The entire disclosure for compensation-related costs for equity-based compensation, which may include disclosure of policies, compensation plan details, allocation of equity compensation, incentive distributions, equity-based arrangements to obtain goods and services, deferred compensation arrangements, employee stock ownership plan details and employee stock purchase plan details. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -URI http://asc.fasb.org/topic&trid=2228938 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -URI http://asc.fasb.org/subtopic&trid=2208855 + Details
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