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Stock-Based Compensation (Tables) | 9 Months Ended
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Sep. 30, 2019
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] |
Stock-Based Compensation Expense | We recognized total stock-based compensation expense in our Condensed Consolidated Statements of Operations as follows (in thousands):
| Three months ended September 30, |  | Nine months ended September 30,
| 2019 |  | 2018 |  | 2019 |  | 2018
Cost of goods sold | $ | 1,119 |  |  | $ | 1,176 |  |  | $ | 3,208 |  |  | $ | 3,470 |
Research and development | 15,680 |  |  | 15,365 |  |  | 47,549 |  |  | 40,449 |
General and administrative | 8,081 |  |  | 6,746 |  |  | 24,030 |  |  | 19,976 |
Total stock-based compensation | $ | 24,880 |  |  | $ | 23,287 |  |  | $ | 74,787 |  |  | $ | 63,895 |
Share-based Compensation, Activity | We issued stock-based awards and resulting shares of our common stock as follows (shares in thousands):
| Three months ended September 30, |  | Nine months ended September 30,
| 2019 |  | 2018 |  | 2019 |  | 2018
Options granted | 131 |  |  | 190 |  |  | 246 |  |  | 929 |
Weighted-average grant-date fair value of options granted | $ | 13.43 |  |  | $ | 30.52 |  |  | $ | 15.81 |  |  | $ | 39.28 |
RSUs granted | 316 |  |  | 152 |  |  | 712 |  |  | 558 |
Weighted-average grant-date fair value of RSUs granted | $ | 28.00 |  |  | $ | 57.27 |  |  | $ | 31.80 |  |  | $ | 54.49 |
Shares issued under equity compensation plans | 820 |  |  | 642 |  |  | 2,256 |  |  | 5,248 |

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- Definition Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=115993241&loc=d3e301413-122809 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5047-113901 + Details
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- Definition Tabular disclosure for share-based compensation plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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