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License and Collaboration Agreements - Additional Information (Detail) - USD ($) |  |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 76 Months Ended
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Feb. 13, 2018 | Aug. 23, 2017 | Dec. 31, 2018 | Apr. 30, 2018 | Jan. 31, 2018 | Nov. 30, 2017 | Sep. 30, 2017 | Aug. 31, 2017 | Sep. 30, 2016 | Mar. 31, 2016 | Sep. 30, 2019 | Sep. 30, 2018 | Dec. 31, 2010 | Sep. 30, 2019 | Sep. 30, 2018 | Dec. 31, 2015
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue recognized in period related to performance in prior periods |  |  |  |  |  |  |  |  |  |  | $ 20,500,000 | $ 18,600,000 |  | $ 56,600,000 | $ 64,200,000 |
Deferred revenue, current portion |  |  | $ 13,892,000 |  |  |  |  |  |  |  | 8,392,000 |  |  | 8,392,000 |  |
Deferred revenue, less current portion |  |  | 10,744,000 |  |  |  |  |  |  |  | 6,779,000 |  |  | 6,779,000 |  |
Potential future additional development and regulatory milestones |  |  |  |  |  |  |  |  |  |  | 1,700,000,000 |  |  | 1,700,000,000 |  |
Accounts receivable |  |  | 43,213,000 |  |  |  |  |  |  |  | 41,205,000 |  |  | 41,205,000 |  |
Revenue recognized from contracts with customers |  |  |  |  |  |  |  |  |  |  | 29,218,000 | 27,762,000 |  | 80,755,000 | 1,153,497,000 |
Deferred revenue |  |  | 24,636,000 |  |  |  |  |  |  |  | 15,171,000 |  |  | 15,171,000 |  |
NKTR-358 | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  |  |  |  |  | 3,100,000 |  |  | 3,100,000 |  |
BMS Collaboration Agreement | NKTR-214 | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments received from license agreements |  |  |  | $ 1,000,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |
Global commercialization profits and losses sharing percentage | 65.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing production costs | 65.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum total additional cash payments receivable upon achievement of certain development and regulatory milestones |  |  |  | 1,400,000,000 |  |  |  |  |  |  |  |  |  |  |  |
BMS Collaboration Agreement | NKTR-214 | Nektar's | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eligible additional cash payments receivable upon achievement of certain sales milestones |  |  |  | $ 350,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |
BMS Collaboration Agreement | NKTR-214 | Nektar's | Opdivo |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing development costs | 32.50% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
BMS Collaboration Agreement | NKTR-214 | Nektar's | Opdivo and Yervoy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing development costs | 22.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
NKTR-358 | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Received upfront and milestone payment |  |  |  |  |  |  | $ 150,000,000.0 |  |  |  |  |  |  |  |  |
Percentage of sharing in Phase 2 development costs |  | 25.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nektar |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of upfront payment, market access milestones, royalties and sales milestones |  |  |  |  |  |  |  |  |  | 40.00% |  |  |  |  |  |
Baxalta Incorporated/Takeda | Hemophilia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Received under right to sublicense agreement |  |  |  |  |  | $ 12,000,000.0 |  |  |  |  |  |  |  |  |  |
Baxalta Incorporated/Takeda | Hemophilia | Annual Sales Level Milestone |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue recognized from contracts with customers |  |  | $ 10,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |
Baxalta Incorporated/Takeda | Hemophilia | European Union |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments received from license agreements |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 10,000,000.0 |
Revenue recognized from contracts with customers |  |  |  |  | $ 10,000,000.0 |  |  |  |  |  |  |  |  |  | 10,000,000.0 |
Bristol-Myers Squibb Company | Purchase Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued (in shares) |  |  |  | 8,284,600 |  |  |  |  |  |  |  |  |  |  |  |
Sale of stock consideration received |  |  |  | $ 850,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |
Bristol-Myers Squibb Company | NKTR-214 | Research and Development Expense |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Reimbursement of expenses |  |  |  |  |  |  |  |  |  |  | 28,300,000 | $ 18,900,000 |  | 81,400,000 | 42,800,000 |
Bristol-Myers Squibb Company | BMS Collaboration Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Accounts receivable |  |  |  |  |  |  |  |  |  |  | 27,700,000 |  |  | 27,700,000 |  |
Bristol-Myers Squibb Company | BMS Collaboration Agreement | Purchase Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total consideration received under agreements |  |  |  | 1,850,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Estimated fair value of shares |  |  |  | $ 790,200,000 |  |  |  |  |  |  |  |  |  |  |  |
Closing date price of common stock (in dollars per share) |  |  |  | $ 99.36 |  |  |  |  |  |  |  |  |  |  |  |
Remaining amount allocated to transaction price |  |  |  | $ 1,059,800,000 |  |  |  |  |  |  |  |  |  |  |  |
Potential future development, regulatory and sales milestones |  |  |  | $ 1,800,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Bristol-Myers Squibb Company | BMS Collaboration Agreement | NKTR-214 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Global commercialization profits and losses sharing percentage | 35.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing production costs | 35.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amount recognized for granting licenses |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,059,800,000 |
Bristol-Myers Squibb Company | BMS Collaboration Agreement | NKTR-214 | Opdivo |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing development costs | 67.50% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Bristol-Myers Squibb Company | BMS Collaboration Agreement | NKTR-214 | Opdivo and Yervoy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing development costs | 78.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Bristol-Myers Squibb Company | Clinical Trial Agreement | NKTR-214 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of out-of-pocket costs to be reimbursed by partner |  |  |  |  |  |  |  |  | 50.00% |  |  |  |  |  |  |
Eli Lilly and Company | NKTR-358 | ASC 606 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue recognized from contracts with customers |  |  |  |  |  |  |  | $ 125,900,000 |  |  |  |  |  |  |  |
Eli Lilly and Company | NKTR-358 License |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amount of transaction price allocated to performance obligation |  |  |  |  |  |  | 125,900,000 |  |  |  |  |  |  |  |  |
Eli Lilly and Company | NKTR-358 | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential future additional development and regulatory milestones |  | $ 250,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | NKTR-358 | Nektar's |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of regulatory milestones payments will be reduced under certain conditions |  | 50.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of regulatory milestones payments will be reduced if conditions occur |  | 75.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | NKTR-358 | Nektar's | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of funding phase 3 development costs on an indication by indication basis borne |  | 25.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | NKTR-358 | Nektar's | Minimum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of funding phase 3 development costs on an indication by indication basis borne |  | 0.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eli Lilly and Company | Phase 1 Clinical Development | NKTR-358 License |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amount of transaction price allocated to performance obligation |  |  |  |  |  |  | 17,600,000 |  |  |  |  |  |  |  |  |
Eli Lilly and Company | Drug Product Development | NKTR-358 License |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amount of transaction price allocated to performance obligation |  |  |  |  |  |  | $ 6,500,000 |  |  |  |  |  |  |  |  |
Eli Lilly | NKTR-358 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of sharing in Phase 2 development costs |  | 75.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amgen, Inc. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Received upfront and milestone payment |  |  |  |  |  |  |  |  |  |  |  |  | $ 50,000,000.0 |  |  |
Amgen, Inc. | ASC 606 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  |  |  |  |  | 5,400,000 |  |  | $ 5,400,000 |  |
AstraZeneca AB | MOVANTIK and MOVENTIG |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Received upfront and milestone payment |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 385,000,000.0
Amount of post approval study expenses eligible for reimbursement |  |  |  |  |  |  |  |  |  |  |  |  |  | 33.00% |  |
Amount of post approval study expenses eligible for reimbursement, maximum |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 35,000,000.0 |  |
Share of expenses |  |  |  |  |  |  |  |  |  |  |  |  |  | 1,700,000 |  |
AstraZeneca AB | AstraZeneca-Kirin |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  |  |  |  |  | 0 |  |  | 0 |  |
Percentage of upfront payment, market access milestone payments, royalties and sales milestone payments from sublicense agreement retained by our collaboration partner |  |  |  |  |  |  |  |  |  | 60.00% |  |  |  |  |  |
Baxalta Inc. / Takeda Pharmaceutical Company Ltd. and other |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  |  |  |  |  | 6,000,000.0 |  |  | 6,000,000.0 |  |
Potential future additional payments for development milestones |  |  |  |  |  |  |  |  |  |  | $ 45,500,000 |  |  | $ 45,500,000 |  |

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