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v3.19.3

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2019 | Sep. 30, 2018
Cash flows from operating activities: |  |
Net income (loss) | $ (327,229) | $ 779,525
Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities: |  |
Non-cash royalty revenue related to sale of future royalties | (27,585) | (24,337)
Non-cash interest expense on liability related to sale of future royalties | 17,853 | 14,808
Stock-based compensation | 74,787 | 63,895
Depreciation and amortization | 9,582 | 7,799
Accretion of discounts, net and other non-cash transactions | (10,421) | (8,136)
Changes in operating assets and liabilities: |  |
Accounts receivable | 2,008 | (16,179)
Inventory | (2,339) | (2,570)
Other assets | 18,127 | (22,087)
Accounts payable | 16,109 | 2,611
Accrued compensation | 13,164 | 19,659
Other accrued expenses | 10,019 | 26,603
Deferred revenue | (9,465) | (10,931)
Other liabilities | 11,932 | 5,104
Net cash provided by (used in) operating activities | (203,458) | 835,764
Cash flows from investing activities: |  |
Purchases of investments | (1,028,883) | (1,944,178)
Maturities of investments | 1,122,902 | 467,658
Sales of investments | 0 | 11,963
Purchases of property, plant and equipment | (22,614) | (5,552)
Sales of property, plant and equipment | 0 | 2,633
Net cash provided by (used in) investing activities | 71,405 | (1,467,476)
Cash flows from financing activities: |  |
Issuance of common stock | 0 | 790,231
Proceeds from shares issued under equity compensation plans | 18,449 | 59,067
Net cash provided by financing activities | 18,449 | 849,298
Effect of exchange rates on cash and cash equivalents | (77) | (87)
Net increase (decrease) in cash and cash equivalents | (113,681) | 217,499
Cash and cash equivalents at beginning of period | 194,905 | 4,762
Cash and cash equivalents at end of period | 81,224 | 222,261
Supplemental disclosures of cash flow information: |  |
Cash paid for interest | 14,229 | 14,701
Operating lease right-of-use assets recognized in exchange for lease liabilities | $ 56,025 | $ 0

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