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Income Taxes - Significant Components of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands | Dec. 31, 2019 | Dec. 31, 2018
--- | --- | ---
Deferred tax assets: |  |
Net operating loss carryforwards | $ 399,361 | $ 300,693
Research and other credits | 128,015 | 116,955
Operating lease liabilities | 36,907 | 0
Stock-based compensation | 30,875 | 21,518
Property, plant and equipment | 5,021 | 2,124
Capitalized research expenses | 3,705 | 8,072
Reserves and accruals | 2,934 | 8,066
Deferred revenue | 1,908 | 4,467
Deferred tax assets before valuation allowance | 608,726 | 461,895
Valuation allowance for deferred tax assets | (575,087) | (460,455)
Total deferred tax assets | 33,639 | 1,440
Operating lease right-of-use assets | (31,718) | 0
Other | (1,725) | (1,270)
Total deferred tax liabilities | (33,443) | (1,270)
Net deferred tax assets | $ 196 | $ 170

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