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Liability Related to the Sale of Future Royalties - Additional Information (Detail) - USD ($) $ in Thousands |  | 1 Months Ended | 3 Months Ended | 12 Months Ended | 70 Months Ended | 94 Months Ended
--- | --- | --- | --- | --- | --- | ---
Feb. 24, 2012 | Feb. 24, 2012 | Mar. 31, 2014 | Mar. 31, 2013 | Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2017 | Dec. 31, 2019
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Royalty agreement contingent payment description |  |  |  |  |  |  |  | As a result of worldwide net sales of MIRCERA® for the 12 month periods ended December 31, 2013 and 2012 not reaching certain minimum thresholds. |  |  |  |
Non-cash royalty revenue related to sale of future royalties |  |  |  |  |  |  |  | $ 36,303 | $ 33,308 | $ 30,531 |  | $ 207,142
Non-cash interest expense on liability related to sale of future royalties |  |  |  |  |  |  |  | $ 25,044 | $ 21,196 | $ 18,869 |  | $ 166,693
Annual interest rate |  |  |  |  | 19.50% | 18.70% | 17.60% |  |  |  | 17.00% |
Prospective interest rate |  |  |  |  | 38.00% | 29.00% | 21.00% |  |  |  |  |
Purchase and Sale Agreement with RPI |  |  |  |  |  |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from sale of royalty rights | $ 124,000 | $ 124,000 |  |  |  |  |  |  |  |  |  |
Transaction costs related to sale of potential future royalties | $ 4,400 |  |  |  |  |  |  |  |  |  |  |
Payment made for milestone not achieved year two |  |  | $ 7,000 |  |  |  |  |  |  |  |  |
Payment made for milestone not achieved year one |  |  |  | $ 3,000 |  |  |  |  |  |  |  |

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