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v3.20.1

Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2020 | Mar. 31, 2019
Revenue: |  |
Total revenue | $ 50,573 | $ 28,222
Operating costs and expenses: |  |
Cost of goods sold | 3,811 | 5,440
Research and development | 108,987 | 118,463
General and administrative | 26,217 | 25,006
Impairment of assets and other costs for terminated program | 45,189 | 0
Total operating costs and expenses | 184,204 | 148,909
Loss from operations | (133,631) | (120,687)
Non-operating income (expense): |  |
Interest expense | (6,204) | (5,226)
Non-cash interest expense on liability related to sale of future royalties | (6,968) | (6,065)
Interest income and other income (expense), net | 8,352 | 12,483
Total non-operating income (expense), net | (4,820) | 1,192
Loss before provision for income taxes | (138,451) | (119,495)
Provision for income taxes | 200 | 137
Net loss | $ (138,651) | $ (119,632)
Basic and diluted net loss per share (in dollars per share) | $ (0.78) | $ (0.69)
Weighted average shares outstanding used in computing basic and diluted net loss per share (in shares) | 177,185 | 173,859
Product sales |  |
Revenue: |  |
Total revenue | $ 3,444 | $ 4,398
Royalty revenue |  |
Revenue: |  |
Total revenue | 9,719 | 11,390
Non-cash royalty revenue related to sale of future royalties |  |
Revenue: |  |
Total revenue | 9,895 | 8,230
License, collaboration and other revenue |  |
Revenue: |  |
Total revenue | $ 27,515 | $ 4,204

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