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Stock-Based Compensation (Tables) | 9 Months Ended
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Sep. 30, 2020
Share-based Payment Arrangement [Abstract] |
Stock-Based Compensation Expense | We recognized total stock-based compensation expense in our Condensed Consolidated Statements of Operations as follows (in thousands):
| Three months ended September 30, |  | Nine months ended September 30,
| 2020 |  | 2019 |  | 2020 |  | 2019
Cost of goods sold | $ | 744 |  |  | $ | 1,119 |  |  | $ | 2,168 |  |  | $ | 3,208 |
Research and development | 14,212 |  |  | 15,680 |  |  | 43,826 |  |  | 47,549 |
General and administrative | 8,711 |  |  | 8,081 |  |  | 25,255 |  |  | 24,030 |
Impairment of assets and other costs for terminated program | — |  |  | — |  |  | 1,025 |  |  | — |
Total stock-based compensation | $ | 23,667 |  |  | $ | 24,880 |  |  | $ | 72,274 |  |  | $ | 74,787 |
Share-based Compensation, Activity | We issued stock-based awards and resulting shares of our common stock as follows (shares in thousands):
| Three months ended September 30, |  | Nine months ended September 30,
| 2020 |  | 2019 |  | 2020 |  | 2019
Options granted | 233 |  |  | 131 |  |  | 282 |  |  | 246 |
Weighted-average grant-date fair value of options granted | $ | 11.64 |  |  | $ | 13.43 |  |  | $ | 11.68 |  |  | $ | 15.81 |
RSUs granted | 693 |  |  | 316 |  |  | 1,213 |  |  | 712 |
Weighted-average grant-date fair value of RSUs granted | $ | 21.56 |  |  | $ | 28.00 |  |  | $ | 21.04 |  |  | $ | 31.80 |
Shares issued under equity compensation plans | 584 |  |  | 820 |  |  | 2,889 |  |  | 2,256 |

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