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Liabilities Related to the Sales of Future Royalties - Additional Information (Detail) - USD ($) $ in Thousands |  |  |  |  | 1 Months Ended | 12 Months Ended | 106 Months Ended
--- | --- | --- | --- | --- | --- | --- | ---
Dec. 31, 2020 | Dec. 30, 2020 | Dec. 16, 2020 | Feb. 24, 2012 | Mar. 31, 2014 | Mar. 31, 2013 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2020
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |  |  |  |
Royalty agreement contingent payment description |  |  |  |  |  |  | As a result of worldwide net sales of MIRCERA® for the 12 month periods ended December 31, 2013 and 2012 not reaching certain minimum thresholds. |  |  |
Non-cash royalty revenue |  |  |  |  |  |  | $ 48,563 | $ 36,303 | $ 33,308 | $ 255,705
Non-cash interest expense on liability related to sale of future royalties |  |  |  |  |  |  | 30,267 | $ 25,044 | $ 21,196 | 196,960
Purchase and Sale Agreement 2012 |  |  |  |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |  |  |  |
Proceeds from sale of royalty rights |  |  |  | $ 124,000 |  |  |  |  |  |
Transaction costs related to sale of potential future royalties |  |  |  | $ 4,400 |  |  |  |  |  |
Non-cash royalty revenue |  |  |  |  |  |  | 37,938 |  |  | 245,080
Non-cash interest expense on liability related to sale of future royalties |  |  |  |  |  |  | 30,267 |  |  | $ 196,960
Purchase and Sale Agreement 2020 |  |  |  |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |  |  |  |
Proceeds from sale of royalty rights |  | $ 150,000 |  |  |  |  |  |  |  |
Transaction costs related to sale of potential future royalties |  | $ 3,800 |  |  |  |  |  |  |  |
Non-cash royalty revenue | $ 10,625 |  |  |  |  |  | 10,625 |  |  |
Non-cash interest expense on liability related to sale of future royalties | $ 0 |  |  |  |  |  | $ 0 |  |  |
Payment of transaction related to purchase and sale agreement |  |  | $ 210,000 |  |  |  |  |  |  |
Payment of transaction related to purchase and sale agreement if threshold is not achieved |  |  | 240,000 |  |  |  |  |  |  |
Minimum transaction royalties payments needed to pay the difference between the 2025 threshold and 2020 transaction royalties |  |  | $ 208,000 |  |  |  |  |  |  |
Purchase and Sale Agreement with RPI |  |  |  |  |  |  |  |  |  |
Liability Related to the Sale of Future Royalties [Line Items] |  |  |  |  |  |  |  |  |  |
Payment made for milestone not achieved year two |  |  |  |  | $ 7,000 |  |  |  |  |
Payment made for milestone not achieved year one |  |  |  |  |  | $ 3,000 |  |  |  |

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