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Stock-Based Compensation (Tables) | 6 Months Ended
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Jun. 30, 2021
Share-based Payment Arrangement [Abstract] |
Stock-Based Compensation Expense | We recognized total stock-based compensation expense in our Condensed Consolidated Statements of Operations as follows (in thousands):
| Three months ended June 30, |  | Six months ended June 30,
| 2021 |  | 2020 |  | 2021 |  | 2020
Cost of goods sold | $ | 716 |  |  | $ | 664 |  |  | $ | 1,443 |  |  | $ | 1,424 |
Research and development | 13,479 |  |  | 14,161 |  |  | 27,641 |  |  | 29,614 |
General and administrative | 9,519 |  |  | 8,546 |  |  | 18,528 |  |  | 16,544 |
Impairment of assets and other costs for terminated program | — |  |  | — |  |  | — |  |  | 1,025 |
Total stock-based compensation | $ | 23,714 |  |  | $ | 23,371 |  |  | $ | 47,612 |  |  | $ | 48,607 |
Share-based Compensation, Activity | We issued stock-based awards and resulting shares of our common stock as follows (shares in thousands):
| Three months ended June 30, |  | Six months ended June 30,
| 2021 |  | 2020 |  | 2021 |  | 2020
Options granted | 157 |  |  | — |  |  | 278 |  |  | 49 |
Weighted-average grant-date fair value of options granted | $ | 9.78 |  |  | $ | — |  |  | $ | 10.23 |  |  | $ | 11.88 |
RSUs granted | 520 |  |  | 275 |  |  | 887 |  |  | 520 |
Weighted-average grant-date fair value of RSUs granted | $ | 18.20 |  |  | $ | 21.65 |  |  | $ | 19.21 |  |  | $ | 20.36 |
Shares issued under equity compensation plans | 1,483 |  |  | 947 |  |  | 3,682 |  |  | 2,305 |

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